Tetrodotoxins in the flatworm Planocera multitentaculata.

Toxicon

Department of Marine Science and Resources, Nihon University, Fujisawa, Kanagawa, 252-0880, Japan. Electronic address:

Published: September 2022

The marine polyclad flatworm Planocera multitentaculata is known to possess high levels of tetrodotoxin (TTX), but the presence of TTX analogues in the species has been unexplored. In this study, TTX and several analogues such as 5,6,11-trideoxyTTX, monodeoxyTTXs, dideoxyTTXs, and 11-norTTX-6(S)-ol were identified in three adults and egg plates of P. multitentaculata using high resolution liquid chromatography-mass spectrometry (HR-LC/MS) for the first time.

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Source
http://dx.doi.org/10.1016/j.toxicon.2022.07.001DOI Listing

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