Isolation, structural elucidation of new phytoecdysteroids from Ajuga decumbens Thunb.

Steroids

Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fujian, China; Xiamen Institute of Rare-earth Materials, Chinese Academy of Sciences, Xiamen, China; University of Chinese Academy of Sciences, Beijing, China. Electronic address:

Published: October 2022

Five new phytoecdysteroids (1, 2, 3, 4, and 5) were isolated from Ajuga decumbens Thunb. planted at Pingtan island of Fujian Province. Their structures were elucidated by NMR(H NMR, C NMR, DEPT, HMBC, HSQC, H-H COSY, ROESY), and HRESIMS. Especially, compound 2 is the epimer of Cyasterone, which was directly confirmed using single crystal X-ray diffraction analysis.

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http://dx.doi.org/10.1016/j.steroids.2022.109089DOI Listing

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