Artificial joints are exposed to loads on a daily basis. Loads on the bone through the artificial joint and the joint's sliding surface shear force may cause implant fixation failure, fatigue fractures, wear of the bearing and foreign body reactions. Artificial joints can experience sudden internal damage, which can be fatal if it occurs during activities performed at high altitudes or in water. The standard design hip prosthesis has a metal femoral stem. Most stem fractures are caused at the proximal one third of the stem by fatigue due to repetitive loading. Femoral stem neck fractures can also occur. To eliminate in vivo prosthesis failures, safety performance preclinical studies evaluate stem body and neck breakage. However, the development of new femoral stems via prototyping and fatigue test verification would require excessive time and money. Therefore, evaluation methods based on numerical analyses, such as finite element analysis (FEA), have been introduced to simulate tests on actual machines. Fatigue strength design verification using FEA can efficiently identify a design that can pass International Organization for Standardization fatigue tests. FEA may also aid with composite implant development by enabling efficient preclinical testing to prove safety using minimal actual fatigue testing. Once a biological safety study of a composite material is performed, a clinical trial can prove its clinical efficacy and safety and device regulatory approval can be requested. This review was created based on a translation of the Japanese review written in the Japanese Journal of Artificial Organs in 2020 (Vol. 49, No. 3, pp. 195-198), with adding some additional contents and references.
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http://dx.doi.org/10.1007/s10047-022-01345-0 | DOI Listing |
Phys Rev Lett
December 2024
Institute of Natural Sciences, School of Mathematical Sciences, MOE-LSC, Shanghai Jiao Tong University, Shanghai 200240, P. R. China.
We present a novel new way-called Schrödingerization-to simulate general (quantum and nonquantum) systems of linear ordinary and partial differential equations (PDEs) via quantum simulation. We introduce a new transform, referred to as the warped phase transformation, where any linear-including nonautonamous-system of ordinary or partial differential equation can be recast into a system of Schrödinger's equations, in real time, in a straightforward way. This approach is not only applicable to PDEs for classical problems but is also useful for quantum problems, including the preparation of quantum ground states and Gibbs thermal states, the simulation of quantum states in random media in the semiclassical limit, simulation of Schrödinger's equation in a bounded domain with artificial boundary conditions, and other non-Hermitian physics.
View Article and Find Full Text PDFPhys Rev Lett
December 2024
New Cornerstone Science Laboratory, Department of Physics, University of Hong Kong, Hong Kong, China.
The ability to generate Landau levels using a pseudomagnetic field (PMF), also called an artificial gauge field, opens up new pathways for exploring fundamental physics and developing novel applications based on topological protection. In this Letter, we simultaneously realize a PMF and a pseudoelectric field (PEF) on a photonic crystal platform and observe a rainbow effect of the Landau zeroth modes. While a PMF induces a series of discretized Landau levels of photons in a similar way as the quantum Hall effect for electrons, a PEF breaks the degeneracy of the flat band of Landau levels over a broad range.
View Article and Find Full Text PDFJ Phys Chem B
December 2024
Department of Earth and Planetary Sciences and Origins of Life Initiative, Harvard University, 20 Oxford Street, Cambridge, Massachusetts 02138, United States.
We report the interactions and dynamics of chemically powered soft swimmers that undergo autonomous oscillatory motion. The interaction of autonomous entities is the basis for the development of collective behaviors among biological organisms. Collective behaviors enable organisms to efficiently attain food and coordinate against threats.
View Article and Find Full Text PDFCureus
November 2024
Hematopoiesis, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto, JPN.
Purpose The purpose of this study was to assess the ability of large language models (LLMs) to comprehend the safety management, protection methods, and proper handling of X-rays according to laws and regulations. We evaluated the performance of GPT-4o (OpenAI, San Francisco, CA, USA) and o1-preview (OpenAI) using questions from the 'Operations Chief of Radiography With X-rays' certification examination in Japan. Methods This study engaged GPT-4o and o1-preview in responding to questions from this Japanese certification examination for 'Operations Chief of Radiography With X-rays'.
View Article and Find Full Text PDFACS Nano
December 2024
Institute of Functional Nano and Soft Materials (FUNSOM), Joint International Research Laboratory of Carbon-Based Functional Materials and Devices, Soochow University, Suzhou 215123, P. R. China.
Triboelectrification-based artificial mechanoreceptors (TBAMs) is able to convert mechanical stimuli directly into electrical signals, realizing self-adaptive protection and human-machine interactions of robots. However, traditional contact-electrification interfaces are prone to reaching their deformation limits under large pressures, resulting in a relatively narrow linear range. In this work, we fabricated mechano-graded microstructures to modulate the strain behavior of contact-electrification interfaces, simultaneously endowing the TBAMs with a high sensitivity and a wide linear detection range.
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