Objectives: Syphilis is a sexually transmitted infection (STI) caused by treponema pallidum. Its rash usually affects the trunk and limbs extensively, including the palms and soles of the feet. Secondary syphilis confined to the face is extremely rare.
Methods: We report a case of annular rupioid secondary syphilis, which was misdiagnosed as verruca vulgaris.
Results: The patient's lesions were confined to the face and resembled oyster shells. Her serological tests results were positive for treponema pallidum particle agglutination assay (TPPA) and rapid plasma reagin (RPR) (1:64).
Conclusion: According to epidemiological history, clinical presentation, non-treponemal tests, treponemal tests, and effective benzathine penicillin G treatment, confirmed secondary syphilis.
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http://dx.doi.org/10.1016/j.ijid.2022.07.028 | DOI Listing |
J Clin Aesthet Dermatol
December 2024
Dr. Rosen and Ms. Terrell are with the Dermatology Department, School of Medicine at Baylor College of Medicine in Houston, Texas.
Cureus
November 2024
Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles (UCLA) Health, Los Angeles, USA.
Syphilitic hepatitis is a rare manifestation of a sexually transmitted infection. Given its nonspecific presentation, it is important for clinicians to consider the diagnosis in sexually active patients presenting with elevated liver tests. In this case, a 30-year-old man presented with an itchy rash and was diagnosed with an allergic reaction.
View Article and Find Full Text PDFInt J STD AIDS
December 2024
Shandong First Medical University, Hospital for Skin Diseases, Jinan, China.
We report two cases of secondary syphilis with an isolated papule on the palm as the initial presentation. The clinical manifestations of secondary syphilis can be diverse, with a high rate of misdiagnosis and underdiagnosis. This article presents two patients with a purpose to alert clinicians not to forget the great imitator of syphilis for lesions of uncertain diagnosis.
View Article and Find Full Text PDFCureus
November 2024
Department of Dermatology, Cleveland Clinic Florida, Weston, USA.
Syphilis is a sexually acquired disease that can affect multiple organ systems. Secondary syphilis can cause a wide range of skin manifestations, leading to misdiagnoses. Herein, we present a patient who developed a diffuse maculopapular rash concerning for a drug reaction leading to a dermatology consult.
View Article and Find Full Text PDFAnn Dermatol Venereol
December 2024
Dermatology Department, Edouard Herriot University Hospital, Lyon, France; Dermatology Department, Croix-Rousse University Hospital, Hospices Civils de Lyon, Lyon, France.
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