Past studies of emotion and mood on memory have mostly focused on the learning of emotional material in the laboratory or on the consequences of a punctate catastrophic event. However, the influence of a long-lasting global condition on memory and learning has not been studied. The COVID-19 pandemic unfortunately offered a unique situation to observe the effects of prolonged, negative events on human memory for visual information. One thousand online subjects were asked to remember the details of real-world photographs of objects to enable fine-grained visual discriminations from novel within-category foils. Visual memory performance was invariant across time, regardless of the infection rate in the local or national population, or the subjects' self-reported affective state using the Positive and Negative Affect Schedule (PANAS). Thus, visual memory provides the human brain with storage that is particularly resilient to changes in emotional state, even when those changes are experienced for months longer than any imaginable laboratory procedure.
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http://dx.doi.org/10.1186/s41235-022-00417-2 | DOI Listing |
Mol Imaging Biol
January 2025
Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Purpose: This preclinical study explored the feasibility of assessing P-glycoprotein (P-gp) function in both brain and gastrointestinal (GI) tract of rats using positron emission tomography (PET) following oral administration of [F]MC225. Different oral administration protocols were evaluated, and radioactivity uptake was compared with uptake following intravenous administration.
Procedures: Twelve male Wistar rats were divided into four groups and subjected to intravenous or oral [F]MC225 administration protocols: G (intravenous route), G (oral administration without fasting), G (oral administration with fasting), and G (oral administration with fasting following administration of the P-gp inhibitor tariquidar).
Medicine (Baltimore)
November 2024
Beatty Liver and Obesity Research Program, Inova Fairfax Medical Campus, Falls Church, VA.
Modifiable risk factors associated with cognitive functioning are important for identifying potential targets for intervention development. Although there are a few recognized modifiable risk factors (e.g.
View Article and Find Full Text PDFEarly Hum Dev
January 2025
Department of Neonatology, Máxima Medical Center, Veldhoven, Noord-Brabant, the Netherlands.
Background: Although preterm birth is associated with deficits in both motor and cognitive functioning, the association between early motor skills and cognitive outcomes at a later age remains underexplored.
Aim: To evaluate associations between motor skills at age 5.5 and cognitive functioning at age 8.
Behav Res Methods
January 2025
Department of Psychology, Columbia University, New York, NY, USA.
While viewing a visual stimulus, we often cannot tell whether it is inherently memorable or forgettable. However, the memorability of a stimulus can be quantified and partially predicted by a collection of conceptual and perceptual factors. Higher-level properties that represent the "meaningfulness" of a visual stimulus to viewers best predict whether it will be remembered or forgotten across a population.
View Article and Find Full Text PDFExp Neurobiol
December 2024
Department of Brain and Cognitive Engineering, Korea University, Seoul 02841, Korea.
Research on brain aging using resting-state functional magnetic resonance imaging (rs-fMRI) has typically focused on comparing "older" adults to younger adults. Importantly, these studies have often neglected the middle age group, which is also significantly impacted by brain aging, including by early changes in motor, memory, and cognitive functions. This study aims to address this limitation by examining the resting state networks in middle-aged adults via an exploratory whole-brain ROI-to-ROI analysis.
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