In a clinical contest, it is common to use dedicated phantoms to perform quality assurance test to check the performance of a SPECT system. Some of these phantoms are also used to calibrate the system for dosimetric evaluation of patients undergoing radiometabolic cancer therapy. In this work, a 3D-OSEM reconstructed Lu SPECT dataset of a homogeneous cylindrical phantom is described. This dataset was acquired to investigate the variation of the SPECT calibration factor, counts convergence, noise and uniformity by varying the number of subsets and iterations. In particular, the dataset is composed of images reconstructed using five different numbers of subsets and sixteen different numbers of iterations, for a total of 80 different configurations. The dataset is suitable for comparison with other reconstruction algorithms (e.g. FBP, MLEM, etc.) and radionuclides (e.g. technetium, yttrium). In regards to the uniformity issue, the same dataset allows the user to perform radiomic investigations on the influence of the border effect on the reconstructed images.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287540 | PMC |
| http://dx.doi.org/10.1038/s41597-022-01535-8 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Relationship between physical parameters and visual analysis for assessment of image quality: a multi-center and multi-vendor phantom study in brain SPECT.
Asia Ocean J Nucl Med Biol
January 2025
Department of Radiological Technology, Faculty of Medical Technology, Tokyo, Japan.
Objectives: Brain perfusion single-photon emission computed tomography (SPECT) image quality varies depending on SPECT systems. This study aimed to evaluate the relationship between physical parameters and visual analysis for assessment of the brain SPECT image quality. We conducted our phantom study under various conditions in a multi-center and multi-vendor study.
View Article and Find Full Text PDFFabrication of 3D printed hollow spheres for quality control and feasibility for use with xSPECT bone.
Phys Eng Sci Med
December 2024
Department of Medical Imaging and Nuclear Medicine, Gosford Hospital, Building K3, Gosford, NSW, Australia.
Quantitative accuracy and constancy of Siemens xSPECT Bone quantitative reconstruction algorithm (xBone) can be monitored using activity-filled hollow spheres, which could be 3D printed (3DP) to increase accessibility to phantoms. One concern is that 3D prints can have air gaps in the walls which may pose issues for attenuation correction and xBone tissue zone mapping. This study assessed the feasibility of using 3DP spheres (3DP-S) with materials PLA, PETG and Resin as substitutes for commercial hollow spheres (C-S).
View Article and Find Full Text PDFAn Evaluation of 90Y Bremsstrahlung SPECT Image Quality in the Presence of 99mTc: A Technical Perspective on Same-Day Radioembolization.
Curr Oncol
November 2024
Department of Radiology and Nuclear Medicine, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.
In same-day radioembolization, 99mTc-MAA SPECT/CT, 90Y radioembolization, and post-treatment 90Y SPECT/CT procedures are conducted on the same-day, resulting in a dual-isotope environment of 90Y and 99mTc during post-treatment imaging. This study aimed to quantify the impact of 99mTc on 90Y bremsstrahlung-SPECT/CT image quality and to establish an optimised imaging protocol for both clinical practice, and with advanced reconstruction techniques. Utilising a NEMA IQ phantom, contrast recovery coefficients (CRCs) were measured to evaluate the 90Y image quality degradation caused by 99mTc.
View Article and Find Full Text PDFAsymptomatic multifocal avascular necrosis, a commonly overlooked finding in patients with systemic lupus erythematosus.
BMC Rheumatol
December 2024
Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Background: In patients with Systemic lupus erythematosus (SLE), osteonecrosis of various joints is a debilitating complication associated with the disease and its treatment, in which a considerable proportion of osteonecrosis may be asymptomatic. Recognizing the crucial role of early and timely detection, as well as appropriate management of asymptomatic osteonecrosis, in preventing joint destruction, we conducted a study to evaluate the prevalence of asymptomatic osteonecrosis in SLE patients who have already been diagnosed with symptomatic osteonecrosis. Additionally, we aimed to examine the relationship between proposed risk factors of osteonecrosis and the development of asymptomatic osteonecrosis.
View Article and Find Full Text PDFComputationally efficient collimator-detector response compensation in high energy SPECT using 1D convolutions and rotations.
Phys Med Biol
December 2024
Radiology and Physics, The University of British Columbia, 6224 Agricultural Rd, Vancouver, British Columbia, V6T 1Z4, CANADA.
Objective: Modeling of the collimator-detector response (CDR) in SPECT reconstruction enables improved resolution and accuracy, and is thus important for quantitative imaging applications such as dosimetry. The implementation of CDR modeling, however, can become a computational bottleneck when there are substantial components of septal penetration and scatter in the acquired data, since a direct convolution-based approach requires large 2D kernels. This work proposes a 1D convolution and rotation-based CDR model that reduces reconstruction times but maintains consistency with models that employ 2D convolutions.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!