Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286526PMC
http://dx.doi.org/10.1002/ctm2.981DOI Listing

Publication Analysis

Top Keywords

neuron-inducing therapy
4
therapy embryonic
4
embryonic neural
4
neural progenitor
4
progenitor cells
4
cells embedding
4
embedding positively
4
positively charged
4
charged gold
4
gold nanoparticles
4

Similar Publications

In this study, we aimed to investigate the recovery after traumatic spinal cord injury (SCI) by inducing cellular differentiation of transplanted neural stem cells (NSCs) into neurons. We dissociated NSCs from the spinal cords of Fisher 344 rat embryos. An injectable gel crosslinked with glycol chitosan and oxidized hyaluronate was used as a vehicle for NSC transplantation.

View Article and Find Full Text PDF

Effects on differentiation of embryonic ventral midbrain progenitors by Lmx1a, Msx1, Ngn2, and Pitx3.

J Neurosci

April 2008

Neuronal Survival Unit, Department of Experimental Medical Science, 221 84 Lund, Sweden.

Neurons derived from neural stem cells could potentially be used for cell therapy in neurodegenerative disorders, such as Parkinson's disease. To achieve controlled differentiation of neural stem cells, we expressed transcription factors involved in the development of midbrain dopaminergic neurons in rat and human neural progenitors. Using retroviral-mediated transgene delivery, we overexpressed Lmx1a (LIM homeobox transcription factor 1, alpha), Msx1 (msh homeobox homolog 1), Ngn2 (neurogenin 2), or Pitx3 (paired-like homeodomain transcription factor 3) in neurospheres derived from embryonic day 14.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!