With the improvement of sanitation, the infection rate of hookworm is greatly reduced and the severe infected case is rarely reported. Combined morphological and molecular biological examinations, a severe hookworm infection patient was diagnosed in Department of Laboratorial Examination, Quanzhou First Affiliated Hospital of Fujian Medical University. The morphological methods such as direct fecal smear microscopy, saturated brine flotation and hookworm larvae culture methods were used to identify the eggs and larvae from stool samples of the patient. There were a large number of hookworm eggs in patient's stool samples, and the average count was 60 840 per gram by modified Kato method, which belonged to severe hookworm infection. Meanwhile, to distinguish the hookworm species, the semi-nested RT-PCR assay was employed to detect hookworm internal transcribed spacer series from eggs in patient's stool samples, and the result showed that the hookworm species was confirmed to be .
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http://dx.doi.org/10.11817/j.issn.1672-7347.2022.210593 | DOI Listing |
Cureus
October 2024
Department of Microbiology, Thanjavur Medical College, Thanjavur, IND.
A parasitic worm is commonly referred to as a helminth. There are two types of helminths: Nematoda, or roundworms, and Platyhelminthes, or flatworms (flukes and tapeworms). While some are very huge, measuring more than one meter in length, many are rather large.
View Article and Find Full Text PDFJ Infect
November 2024
Hospital for Tropical Diseases, Capper Street, London, WC1E 6JB, UK; London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK. Electronic address:
Eosinophilia is a common finding in returning travellers, migrants and other travelling groups. In this setting it often indicates an underlying helminth infection. Infections associated with eosinophilia are frequently either asymptomatic or associated with non-specific symptoms but some can cause severe disease.
View Article and Find Full Text PDFBMC Infect Dis
October 2024
College of medicine and health sciences, medical laboratory department, Injibara University, Injibara, Ethiopia.
Background: Anemia is a common complication of HIV infected children and it is enabling HIV disease progression, and decreasing survival. In Ethiopia, there is limited evidence on the prevalence of anemia and its associated factors among HIV infected children particularly in the Awi Zone. Therefore, this study aimed to assess the magnitude and associated factors of anemia among HIV infected children on ART aged from 6 months to 15 year-old in ART Clinic, Awi-Zone, Ethiopia.
View Article and Find Full Text PDFGut Microbes
October 2024
Department of Medicine, University of Otago, Wellington, New Zealand.
Infecting humans with controlled doses of helminths, such as human hookworm (termed hookworm therapy), is proposed to prevent or treat various intestinal and extraintestinal diseases. However, full-scale clinical trials examining hookworm therapy are limited by the inability to scale-up the production of hookworm larvae to infect sufficient numbers of patients. With the aim of overcoming this challenge, this study infected four healthy individuals with hookworm larvae that had been reanimated from cryopreserved eggs to examine their viability and immunogenicity.
View Article and Find Full Text PDFTrop Doct
October 2024
Professor, Command Hospital Air Force Bengaluru, Bengaluru, KA, India.
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