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| http://dx.doi.org/10.1186/s12957-022-02690-3 | DOI Listing |
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New connective tissue structure of the wrist area - research on fetal material.
Folia Morphol (Warsz)
January 2025
Department of Human Morphology and Embryology, Division of Anatomy, Wroclaw Medical University, Wrocław, Poland.
The correct function of the upper limb depends on the cooperation and coordination of the muscular and skeletal systems as well as the connective tissue elements present in it. Connective tissue forms fascia, connective tissue membranes and ligaments. Connective tissue mostly develops from the mesenchyme.
View Article and Find Full Text PDFHemophilia A is a clotting disorder due to factor VIII deficiency, leading to prolonged bleeding. Acquired hemophilia A results from the immune system attacking factor VIII, typically occurring later in life. Factor V Leiden is a genetic mutation causing abnormal blood clot formation, primarily in veins.
View Article and Find Full Text PDFSKP1-CUL1-F-box: Key molecular targets affecting disease progression.
FASEB J
January 2025
Department of Geriatrics, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China.
The correct synthesis and degradation of proteins are vital for numerous biological processes in the human body, with protein degradation primarily facilitated by the ubiquitin-proteasome system. The SKP1-CUL1-F-box (SCF) E3 ubiquitin ligase, a member of the Cullin-RING E3 ubiquitin ligase (CRL) family, plays a crucial role in mediating protein ubiquitination and subsequent 26S proteasome degradation during normal cellular metabolism. Notably, SCF is intricately linked to the pathogenesis of various diseases, including malignant tumors.
View Article and Find Full Text PDFCreation of a Tibia Extension Model With a Perforated Ilizarov Ring System: An Experimental Study in Rats.
Cureus
December 2024
Department of Orthopaedics and Traumatology, Gaziantep University Faculty of Medicine, Gaziantep, TUR.
Distraction osteogenesis is a valuable clinical technique used to address length discrepancies in long bone deformities. This procedure involves performing an osteotomy at an appropriate site in the bone and correcting the deformity through an extension system. This research aims to investigate the efficacy of a newly developed device for use in rat tibias and to provide an alternative to existing devices used in animal experiments.
View Article and Find Full Text PDFEvaluation of artificial intelligence-based autosegmentation for a high-performance cone-beam computed tomography imaging system in the pelvic region.
Phys Imaging Radiat Oncol
January 2025
Department of Radiotherapy, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Background And Purpose: A novel ring-gantry cone-beam computed tomography (CBCT) imaging system shows improved image quality compared to its conventional version, but its effect on autosegmentation is unknown. This study evaluates the impact of this high-performance CBCT on autosegmentation performance, inter-observer variability, contour correction times and delineation confidence, compared to the conventional CBCT.
Materials And Methods: Twenty prostate cancer patients were enrolled in this prospective clinical study.
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