CD8 T cells: An ineffective armor against prolonged COVID-19 in cancer patients.

Cell Rep Med

Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Department of Medicine, Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address:

Published: July 2022

In a diverse cohort of cancer patients, Lyudovyk et al. show that persistent COVID-19 infection is associated with weaker humoral responses and increased CD8 T cell responses that are ineffective in clearing virus, particularly in patients receiving B cell-depleting therapies.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9233996PMC
http://dx.doi.org/10.1016/j.xcrm.2022.100695DOI Listing

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