The dominoes fall after long-term antibiotic exposure.

Cell Host Microbe

Department of Molecular & Biomedical Sciences, University of Maine, Orono, ME, USA; Graduate School of Biomedical Sciences, University of Maine, Orono, ME, USA. Electronic address:

Published: July 2022

Broad-spectrum antibiotics should prevent disease, right? In this issue of Cell Host & Microbe, Drummond et al. turn logic on its head and show they actually drive more deadly invasive fungal-bacterial systemic co-infection. Prophylactic antibiotics increase susceptibility to these infections by targeting the commensal microbes required for gut-derived IL-17-mediated immunity.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598949PMC
http://dx.doi.org/10.1016/j.chom.2022.06.007DOI Listing

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The dominoes fall after long-term antibiotic exposure.

Cell Host Microbe

July 2022

Department of Molecular & Biomedical Sciences, University of Maine, Orono, ME, USA; Graduate School of Biomedical Sciences, University of Maine, Orono, ME, USA. Electronic address:

Broad-spectrum antibiotics should prevent disease, right? In this issue of Cell Host & Microbe, Drummond et al. turn logic on its head and show they actually drive more deadly invasive fungal-bacterial systemic co-infection. Prophylactic antibiotics increase susceptibility to these infections by targeting the commensal microbes required for gut-derived IL-17-mediated immunity.

View Article and Find Full Text PDF

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