Type 1 CD8 T cells (Tc1s) have been implicated in liver injury in autoimmune hepatitis (AIH) through mechanisms that have so far been unclear. In this issue of Cell Host & Microbe, Pandey et al. show that the aryl hydrocarbon receptor ligand-producing pathobiont Lactobacillus reuteri induces Tc1-mediated AIH-like pathology in mice with Tet-methylcytosine-dioxygenase-2 deficiency.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520518 | PMC |
| http://dx.doi.org/10.1016/j.chom.2022.06.004 | DOI Listing |
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