For investigating the correlation with spectral CT imaging parameters and occult lymph nodes metastasis in sufferers with isolated lung adenocarcinoma. The clinic cases data of 352 sufferers with isolated lung adenocarcinoma from January 2019 to January 2022 were assembled. In line with whether the sufferers had occult lymph nodes metastasis, they were taken as a part in the metastasis group ( = 172) and the nonmetastasis group. All sufferers were scanned by spectral CT with a dual-phase contrast-enhanced method, and the recording of spectral CT imaging parameters in arteriovenous phase, iodine concentration (IC), water concentration (WC), the slope rate of the spectral HU curve (HU), the normalized iodine concentration(NIC), the normalized water concentration(NWC), the normalized effective atomic number (Neff-Z)], and receiver operating characteristic (ROC) were employed to analyze the spectral CT imaging parameters of the arteriovenous phase. Evaluation of occult lymph nodes metastases in sufferers with isolated lung adenocarcinoma. The IC, NIC, HU, and Neff-Z in the arteriovenous phase spectral CT imaging parameters of the metastasis group were obviously smaller than that of the nonmetastasis group, and the discrepancies were statistically obvious ( < 0.05). The results of ROC curve analysis manifested that the area under the curve (AUC) of HU, IC, NIC, and Neff-Z in the CT parameters of the arterial phase were 0. 840 (95%CI : 0. 796-0.883), 0.763 (95% CI : 0.708-0.818), 0.918 (95% CI : 0.888-0.948), 0.778 (95% CI : 0.731-0.826). The AUCs of HU, IC, NIC, and Neff-Z in the venous phase spectral CT parameters were 0.909 (95% CI : 0.877-0.941), 0.837 (95% CI : 0.792-0.881), and 0.980 (95% CI : 0.968-0.968), respectively. 0.993), 0.792 (95% CI : 0.742∼0.842). Spectral CT imaging parameters have a certain value in evaluating occult lymph nodes metastasis in sufferers with isolated lung adenocarcinoma, which is helpful for doctors to judge the lymph nodes metastasis in sufferers with this disease before surgery.
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http://dx.doi.org/10.1155/2022/5472446 | DOI Listing |
Pol J Vet Sci
June 2024
Department and Clinic of Animal Surgery, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, Głęboka 30, 20-612 Lublin, Poland.
The aim of the study was to determine the thickness of choroidal layers in mixed breed dogs suffering from retinal atrophy (RA) and showing symptoms of progressive retinal atrophy (PRA), with the use of SD-OCT. The study was performed on 50 dogs divided into two groups: 25 dogs diagnosed with retinal atrophy (RA) with PRA symptoms aged 1.5-14 years and 25 healthy dogs aged 2-12 years.
View Article and Find Full Text PDFJ Med Imaging (Bellingham)
January 2025
Okaya City Hospital, Division of Diagnostic Pathology, Okaya, Japan.
Purpose: The color of Papanicolaou-stained specimens is a crucial feature in cytology diagnosis. However, the quantification of color using digital images is challenging due to the variations in the staining process and characteristics of imaging equipment. The dye amount estimation of stained specimens is helpful for quantitatively interpreting the color based on a physical model.
View Article and Find Full Text PDFJ Biomed Opt
December 2024
Shanghai University of Medicine and Health Sciences, College of Medical Instruments, Shanghai, China.
Significance: The eye can be used as a potential monitoring window for screening, diagnosis, and monitoring of neurological diseases. Alzheimer's disease (AD) and vascular cognitive impairment (VCI) are common causes of cognitive impairment and may share many similarities in ocular signs. Multimodal ophthalmic imaging is a technology to quantify pupillary light reaction, retinal reflectance spectrum, and hemodynamics.
View Article and Find Full Text PDFJ Med Imaging (Bellingham)
December 2024
University of Chicago, Department of Radiology, Chicago, Illinois, United States.
Purpose: High soft-tissue contrast imaging is essential for effective radiotherapy treatment. This could potentially be realized using both megavoltage and kilovoltage x-ray sources available on some therapy treatment systems to perform "MV-kV" dual-energy (DE) computed tomography (CT). However, noisy megavoltage images obtained with existing energy-integrating detectors (EIDs) are a limiting factor for clinical translation.
View Article and Find Full Text PDFJ Med Imaging (Bellingham)
December 2024
University of Houston, Department of Physics, Houston, Texas, United States.
Purpose: Photon counting detectors offer promising advancements in computed tomography (CT) imaging by enabling the quantification and three-dimensional imaging of contrast agents and tissue types through simultaneous multi-energy projections from broad X-ray spectra. However, the accuracy of these decomposition methods hinges on precise composite spectral attenuation values that one must reconstruct from spectral micro-CT. Errors in such estimations could be due to effects such as beam hardening, object scatter, or detector sensor-related spectral distortions such as fluorescence.
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