AI Article Synopsis
- Tumor immunotherapy boosts the immune system to fight cancer, but only a few patients see benefits, and some may face immune-related side effects.
- Sonodynamic therapy (SDT) generates harmful substances that can kill tumor cells and support immune function, making it a potential boost for immunotherapy.
- The review highlights recent advancements in combining SDT with immunotherapy, discussing how this partnership could improve cancer treatment outcomes.
Article Abstract
Tumor immunotherapy has become an important means of tumor therapy by enhancing the immune response and triggering the activation of immune cells. However, currently, only a small number of patients respond to immunotherapy alone, and patients may experience immune-related adverse events (irAEs) during the course of treatment. Sonodynamic therapy (SDT) can produce cytotoxic substances to tumor tissue, induce apoptosis and enhance immunity. SDT combined with immunotherapy is considered a promising strategy for cancer treatment. In this mini review, we summarize the role of SDT in immunotherapy in recent years, including the application of SDT-triggered immunotherapy and the combination of SDT and immunotherapy.
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| http://dx.doi.org/10.1007/s00432-022-04190-z | DOI Listing |
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