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Cureus
December 2024
Hematology, Dubai Hospital, Dubai Health, Dubai, ARE.
Bernard-Soulier syndrome (BSS) is a rare qualitative condition of platelets wherein deficiency of platelet surface glycoproteins (GP) Ib, IX, and V forms the Ib-IX-V complex, leading to impaired hemostasis. Although it commonly presents as prolonged bleeding in general, women in the reproductive phase report additional complications during menstruation, pregnancy, and childbirth. In women of reproductive age, menorrhagia is a frequent complaint.
View Article and Find Full Text PDFCureus
December 2024
Obstetrics and Gynaecology, Umm Al-Qura University, Makkah, SAU.
Heliyon
August 2024
Department of Mechatronic Engineering, Atlantic Technological University Sligo, Ash Lane, F91 YW50 Sligo, Ireland.
Background: Gynecological issues and sexually transmitted infections (STIs) pose significant challenges to women's health, particularly in developing nations. These challenges are exacerbated by limited access to modern reproductive healthcare facilities, economic constraints, and entrenched cultural norms. Consequently, most of the Pakistani population relies on traditional ethno-medicinal healthcare systems.
View Article and Find Full Text PDFPediatr Blood Cancer
May 2024
Department of Pediatrics, Pediatric Hematology Oncology, Children's Hospital of Michigan, Detroit, Michigan, USA.
Background: Pediatric venous thromboembolism has increased by 130%-200%, specifically in hospitalized children, and direct oral anticoagulants (DOACs) offer several therapeutic advantages.
Methods: This study aims to evaluate the real-world epidemiological and outcome data from a retrospective review of pediatric patients treated with DOACs from January 1, 2013 to December 31, 2022. In this single-center, IRB-approved study, 65 patients were identified and analyzed using SPSS statistical software, and a descriptive statistical analysis was conducted.
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