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Coronavirus Disease 2019 Vaccine Dosage in Children, Adolescents, and Young Adults: Is Less More? | LitMetric

Coronavirus Disease 2019 Vaccine Dosage in Children, Adolescents, and Young Adults: Is Less More?

Open Forum Infect Dis

Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA.

Published: July 2022

AI Article Synopsis

Article Abstract

The lower efficacy of the COVID-19 mRNA vaccines in 5-11 year old children was unexpected. Neutralizing antibody titers elicited by the vaccines in children, adolescents, and young adults suggest that the lower efficacy is not due to the lower dosage. Confirming the efficacy of these vaccines in children, determining if mRNA vaccination strategies are less effective in younger children, as well as optimizing the dosage, dosing intervals, and number of doses needed in children, adolescents, and young adults are critical to improve vaccination strategies for these populations going forward.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9272428PMC
http://dx.doi.org/10.1093/ofid/ofac222DOI Listing

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