AI Article Synopsis

  • Chronic renal failure, which is a serious kidney problem, is very common in older people, leading to health issues like falls and being hospitalized.
  • A study was done with 1,250 people over 65 years old in Lombardy, Italy, to find out what increases the risk of kidney problems.
  • They found that living alone, earning less than €10,000 a year, taking a lot of medications, and having weak muscles or being fragile can increase the chances of having chronic kidney failure.

Article Abstract

Chronic renal failure is an epidemic in elderly patients. Older population have an increased prevalence of frailty and sarcopenia, associated with a wide range of adverse health outcomes such as falls, hospitalization, disability. Describe the sociodemographic and clinical variables of an elderly Lombard population and identify predictors of renal insufficiency. Cross-sectional observational study conducted in hospitals, in recreational centers for the elderly, in the Universities of the Third Age of the provinces of Milan and Monza-Brianza conducted through a convenience sampling of 1250 subjects over the age of 65. The study identified living alone, annual individual income < € 10,000, polypharmacy, sarcopenia and frailty as predictors of chronic kidney failure. The sample has a mean eGFR of 71.74 mL/min/1.73m2 (SD ± 16.56). Older people living alone are more likely to develop CRI (P = 0.031, confidence interval, CI [1.031-1.905]) as well as having an income < € 10,000 (P = 0.002, CI [0.392-0.923]). Taking more than 11 drugs a day increases the probability of having chronic renal failure by 16 times (P = 0.012, CI [1.155-3.16]). Sarcopenia and frailty increase the likelihood of having chronic renal failure (CRI) (P = 0.001, CI [1.198-2.095]). Identifying predictors of chronic kidney failure is a key step in introducing preventive measures and providing better care to the elderly population.

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