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Combustion-derived carbon nanoparticles cause delayed apoptosis in neutrophil-like HL-60 cells in vitro and in primed human neutrophilic granulocytes ex vivo.
Part Fibre Toxicol
March 2025
IUF - Leibniz Research Institute for Environmental Medicine, Auf'm Hennekamp 50, 40225, Düsseldorf, Germany.
Background: Inhalation of combustion-derived nanoparticles may contribute to the development or exacerbation of inflammatory lung diseases by direct interaction with neutrophilic granulocytes. Earlier studies have shown that exposure of human neutrophils to carbon nanoparticles ex vivo causes a prolongation of cellular life by the reduction of apoptosis rates. Accordingly, reduced neutrophil apoptosis rates were observed in neutrophils from bronchoalveolar lavages from carbon nanoparticle-exposed animals.
View Article and Find Full Text PDFAssociation of short-term exposure to PM and its components with hospital admission for asthma in Shanghai: a time-stratified case-crossover study.
J Asthma
March 2025
Department of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, Zhengzhou, Henan, PR China.
Article Synopsis
- The study investigates the link between short-term exposure to particulate matter (PM) and asthma-related hospital admissions in Shanghai, analyzing data from 930 hospitalized patients between 2018 and 2022.
- Each increase of 10 μg/m³ in various PM components (like BC, NO, NH, SO, and OM) was found to elevate the risk of asthma admissions, particularly affecting women, individuals aged 65 and older, and during colder seasons.
- The findings suggest that reducing exposure to air pollution could help lower asthma hospitalization rates, highlighting the significance of PM components in public health.
Econometric model derived from meta-analysis to estimate VSL and VOLY associated to air pollution at a global level.
J Environ Manage
March 2025
European Commission, Joint Research Centre (JRC), Ispra, Italy.
Association between heavy metal exposure and asthma in adults: Data from the Korean National Health and Nutrition Examination Survey 2008-2013.
PLoS One
March 2025
Department of Occupational Environmental Medicine, Seoul Medical Center, Seoul, Korea.
Risk factors for asthma include genetic, host, and environmental factors such as allergens, smoking, and exposure to chemicals. Heavy metals from air pollution or contaminated water and food can also trigger asthma. This study aimed to identify the biological exposure levels of blood lead, mercury, and cadmium, and determine the association of asthma with single and multiple exposures to these heavy metals using data from the Korean National Health and Nutrition Examination Survey (KNHANES) conducted between 2008 and 2013.
View Article and Find Full Text PDFAssociation of a cleaner-burning stove with blood pressure in adults in rural Malawi.
PLoS One
March 2025
School of Public Health, University of California, Berkeley, California, United States of America.
Background: Hypertension is a leading risk factor for cardiovascular disease, and its association with household air pollution (HAP) in sub-Saharan Africa is understudied.
Main Objective: To investigate the association between blood pressure (BP) and HAP exposure in a population-based cohort in rural Malawi.
Materials And Methods: In the Chikwawa district, the site of a previous randomized controlled trial of a cleaner-burning cookstove intervention (the Cooking and Pneumonia Study or CAPS), we recruited 1,481 randomly selected adults.
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