A new "ESIPT + AIE" based dye of benzothiazole with red emission and a large Stokes shift was constructed by combining 2-(2'-hydroxyphenyl)benzothiazole as the ESIPT unit and α-cyanostilbene as the AIE unit. The compound BACN was found to be a ideal HClO chemosensor, and presented palpable fluorescence and colorimetric responses toward HClO via the HClO-trigged oxidation cleavage of the ethylene bridge activated by the electron withdrawing cyano group. BACN was capable of recognizing HClO rapidly (12 s) and sensitively under physiological conditions, with good selectivity over other biologically pertinent substances. Thanks to strong red emission (λ = 606 nm) and large Stokes shift (213 nm) resulted from the combination of ESIPT and AIE effects, it was successfully utilized for the recognition of exogenous and endogenous HClO in living HeLa cells.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.saa.2022.121601 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Multiple Applications of Chiral Self-Assembled H-BINOL Nanoprobes with AIE-ESIPT Characteristics: Chiral Switching and pH Visualization Detection.
ACS Appl Mater Interfaces
December 2024
College of Chemistry and Chemical Engineering, Nanchang University, Nanchang 330031, China.
- exhibited significant aggregation-induced Emission (AIE) characteristics, including high brightness (αAIE ≈ 40), robust light stability, a substantial Stokes shift (128 nm), and a high signal-to-noise ratio, effectively overcoming aggregation-caused quenching (ACQ). Derived from the axially chiral -H-BINOL, - was synthesized via nucleophilic cyclization and exhibited pronounced self-assembly properties. Through robust intra- and intermolecular hydrogen bonding interactions, - formed diverse supramolecular structures, including spherical flower-like aggregates, hollow-core triangular tubules, hexagonal tubules, and irregular white block-like stacks.
View Article and Find Full Text PDFCoassembly of Dual-Modulated AIE-ESIPT Photosensitizers and UCNPs for Enhanced NIR-Excited Photodynamic Therapy.
Nano Lett
December 2024
Key Laboratory of Superlight Materials and Surface Technology, Ministry of Education, College of Materials Science and Chemical Engineering, Harbin Engineering University, Harbin 150001, P. R. China.
Aggregation-induced emission (AIE) photosensitizers are promising for photodynamic therapy, yet their short excitation wavelengths present a limitation. In this study, we develop a series of organic photosensitizers with dual modulation capabilities based on excited-state intramolecular proton transfer (ESIPT) and AIE. Notably, we synthesize near-infrared (NIR)-excited photosensitive nanoparticles through a coassembly strategy utilizing upconversion nanoparticles (UCNPs) and amphiphilic polymers.
View Article and Find Full Text PDFAn activatable "AIE + ESIPT" fluorescent probe for dual-imaging of lipid droplets and hydrogen peroxide in drug-induced liver injury model.
Anal Chim Acta
January 2025
School of Pharmacy and Food Engineering, Wuyi University, 529020, Jiangmen, PR China. Electronic address:
Background: Drug-induced liver injury (DILI) is one of the most common liver diseases. The crucial role of lipid droplets (LDs) and hydrogen peroxide (HO), two important biomarkers in the pathophysiology of DILI, has spurred considerable efforts to accurately visualize HO and LDs for elucidating their functions in the progression of DILI. However, construction of a single fluorescent probe that is able to simultaneously image HO and LDs dynamics remains to be a challenging task.
View Article and Find Full Text PDFAn interesting aggregation induced red shifted emissive and ESIPT active hydroxycoumarin tagged symmetrical azine: Colorimetric and fluorescent turn on-off-on response towards Cu and Cysteine, real sample analysis and logic gate application.
Spectrochim Acta A Mol Biomol Spectrosc
February 2025
Department of Chemistry, Bharathiar University, Coimbatore-641046, Tamil Nadu, India. Electronic address:
We report a newly synthesized 7-diethylamino-4-hydroxycoumarin tagged symmetrical azine derivative (SHC), with an interesting color transformation from yellowish green to orange via aggregation induced red shifted emissive (117 nm) feature in THF-HO mixture. Interestingly, the single crystal X-ray analysis of this molecule demonstrates that two hydroxycoumarin moieties were present in azine unit, among them one of the coumarin units was exist as enol form and another one transferred to keto form via ground state proton transfer reaction. The optical responses of the compound in different solvents exposed the observation of dual emissive bands which corresponds to the presence of ESIPT phenomenon in SHC molecule.
View Article and Find Full Text PDF4,4'-Sulfonyldianiline Derived Aggregation-Induced Emission Luminogen for the Detection of Ofloxacin.
Chempluschem
September 2024
Department of Chemistry, Sardar Vallabhbhai National Institute Technology, Surat, Gujarat, 395007, India.
The excessive use of antibiotic ofloxacin (Oflx) can cause serious detrimental effects to human health. Therefore, the utmost research priority is required to develop facile methods to detect Oflx. Herein, a V-shaped aggregation-induced emission (AIE) active Schiff base SDANA was introduced for the fluorescent turn-on detection of Oflx.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!