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Possible Lurasidone-Associated Dose-Dependent QTc Prolongation in First-Episode Psychosis. | LitMetric

Possible Lurasidone-Associated Dose-Dependent QTc Prolongation in First-Episode Psychosis.

Psychopharmacol Bull

Naguy, MBBch, MSc, Child/Adolescent Psychiatrist, Al-Manara CAP Centre, Kuwait Centre for Mental Health (KCMH), Jamal Abdul-Nassir St, Shuwaikh, State of Kuwait. Prof. Suliman Al-Khadhari, FRCP(Canada), Consultant Psychiatrist, Professor and Head of Psychiatry Department, Faculty of Medicine, Kuwait University, State of Kuwait. Prof. Saxby Pridmore, MD, Professor of Psychiatry, University of Tasmania, Hobart, Australia.

Published: June 2022

This case is one of the earliest to report on lurasidone-related QTc prolongation in a dose-dependent fashion in CAP population at therapeutic doses. Although these reports remain scarce, it behoves prescribers to be vigilant and mindful of these unusual but serious side effects especially in setting of cumulative risks.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235318PMC

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