AI Article Synopsis

  • SBSEC is a gram-positive bacterium often seen in elderly males with underlying health issues, but five recent cases of intrapartum bacteremia were documented in younger mothers without such conditions.
  • Each case showed signs of chorioamnionitis, and all mothers tested negative for Group B Streptococcus (GBS); the bacterium was treatable with common antibiotics.
  • While all babies were healthy at birth, many needed NICU care for clinical sepsis, indicating that SBSEC may be an emerging threat in childbirth.

Article Abstract

is a gram-positive coccus belonging to the family (SBSEC). Most cases of SBSEC bacteremia are reported in elderly males with underlying hepatobiliary disease and associated with infective endocarditis (IE) or colonic malignancy. The gastrointestinal tract is the most common portal of entry, followed by the urinary tract and hepatobiliary tree. We present 5 cases of intrapartum bacteremia caused reported from the labor unit of our hospital from 2019 to 2021. There was histopathological or microbiological evidence of chorioamnionitis in each case. All the mothers were below the age of 35 years, and none of them had underlying hepatobiliary or colonic disease. All maternal antenatal screenings for (GBS) were negative. All the isolates were susceptible to penicillins, ceftriaxone, carbapenems, and vancomycin. Three of them were treated with ceftriaxone and two with aminopenicillins. Duration of treatment varied from 8 days to 14 days. None of the babies were low birth weight or pre-term. All but one baby had clinical sepsis requiring neonatal intensive care unit (NICU) stay, with one having evidence of meningitis and three respiratory distress syndromes (RDS). None of the babies had bacteremia. All mothers and babies made a complete recovery without any complications. These cases suggest that can be a rare but emerging cause of intrauterine infection complicated by post-partum bacteremia. There is possibility of colonization of maternal genital tract with causing neonatal infection.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263517PMC
http://dx.doi.org/10.1016/j.idcr.2022.e01562DOI Listing

Publication Analysis

Top Keywords

intrauterine infection
8
underlying hepatobiliary
8
bacteremia
5
infection postpartum
4
postpartum bacteremia
4
bacteremia emerging
4
emerging concern
4
concern gram-positive
4
gram-positive coccus
4
coccus belonging
4

Similar Publications

Fetal Tetra-Amelia Birth: A Case Report.

Case Rep Obstet Gynecol

December 2024

Department of Obstetrics and Gynecology, Jimma University School of Medicine, Jimma, Ethiopia.

Fetal limb anomaly presentation varies greatly. It can present as amelia (complete absence of skeletal part of one or more limb), meromelia (partial absence of skeletal part of one or more limb), phocomelia (only rudimentary limb formed), and minor limb disorders like polydactyly. The complete absence of the four fetal limbs is extremely rare.

View Article and Find Full Text PDF

The objective of this systematic review was to characterize the literature regarding the risk factors associated with the development of toxic shock syndrome (TSS) secondary to the use of intrauterine contraceptives (IUCs), as well as patient outcomes. A literature search was conducted spanning origin through December 12, 2022, using Embase and MEDLINE ALL. Primary literature that discussed development of TSS along with the presence of an IUC were included.

View Article and Find Full Text PDF
Article Synopsis
  • Introduction of long-acting injectable cabotegravir (CAB-LA) for HIV prevention showed effectiveness, and this study examines its safety and pharmacokinetics in pregnant women participating in the HPTN 084 trial during a blinded period.
  • In the study, pregnant participants were divided into two groups receiving either CAB-LA or TDF/FTC, with careful monitoring of pregnancy outcomes and maternal adverse events, finding that there was no significant difference in adverse event rates or poor pregnancy outcomes between the two groups.
  • The analysis revealed a total of 57 confirmed pregnancies over 3845 person-years, with 81% resulting in live births, and the study concluded that CAB-LA did not result in significantly different safety or outcomes
View Article and Find Full Text PDF

Assessment of adverse pregnancy outcomes associated with Helicobacter pylori infection.

Sci Rep

December 2024

Department of Gynecology and Obstetrics, Taichung Veterans General Hospital, 1650 Taiwan Boulevard Sect. 4 , Taichung, 40705, Taiwan.

The background of Helicobacter pylori (H. pylori) infection is complex, and its influence on adverse pregnancy outcomes is inconsistently reported. We performed a multi-institutional, retrospective analysis using de-identified electronic health records from the TriNetX Research Network to compare various pregnancy outcomes in women with and those without H.

View Article and Find Full Text PDF

Sex-specific associations between maternal exposure to metal mixtures and fetal growth trajectories: A prospective birth cohort study.

Sci Total Environ

December 2024

Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, 81 Meishan Road, Hefei 230032, China; MOE Key Laboratory of Population Health Across Life Cycle, 81 Meishan Road, Hefei 230032, Anhui, China. Electronic address:

Article Synopsis
  • The study investigates how prenatal exposure to metal mixtures affects fetal growth, focusing on differences between male and female fetuses.
  • Researchers analyzed data from 1,041 pregnant women, measuring 12 metals in maternal blood at various stages of pregnancy and assessing fetal growth through a specific indicator called biparietal diameter (BPD).
  • Findings reveal that cobalt has opposing effects on growth trajectories by sex; it negatively impacts male fetuses while positively affecting females, with significant interactions between metal exposure and sex influencing growth outcomes.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!