Admission Pattern and Treatment Outcome in Pediatric Intensive Care Unit, Tertiary Hospital, Addis Ababa, Ethiopia.

Ethiop J Health Sci

Associate Professor, Pediatric Emergency and Critical Care Medicine, Pediatric Cardiac intensivist, Department of Pediatrics and Child Health, Saint Paul Millennium Medical College, Addis Ababa, Ethiopia.

Published: May 2022

AI Article Synopsis

  • The study examines the clinical profile and outcomes of critically ill children in the Pediatric Intensive Care Unit (PICU) of St Paul's Hospital in Addis Ababa, focusing on admission patterns and associated factors from January 2017 to December 2018.
  • A total of 260 patients were analyzed, revealing a mean age at admission of approximately 4 years, a PICU stay averaging over 7 days, and the most impacted organ systems being the central nervous and respiratory systems.
  • The study found a mortality rate of 21.1%, with post-cardiopulmonary resuscitation admissions and mechanical ventilation identified as significant predictors of mortality, highlighting the need for improved PICU resources and staffing to enhance patient outcomes.

Article Abstract

Background: Knowledge of the clinical profile and outcomes of critically ill children admitted to Pediatric Intensive Care Unit (PICU) in developing countries aids with the identification of priorities and the resources needed to improve the outcome of critically ill patients. This study aimed to assess the admission pattern, outcomes, and associated factors of patients admitted to the PICU of St Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.

Methods: Institutional-based cross-sectional study was done. Data was collected through chart abstraction from patients admitted to the PICU between January 2017 and December 2018. SPSS 20.0 was used to analyze the data. Descriptive statistics, cross-tabulations, and logistic regressions were used.

Results: A total of 260 pediatric patients were analyzed. The mean age at admission was 48.13 ± 53.65 months, with M: F ratio of 1.4:1. The mean and median duration of PICU stay was 7.26 ±6.87 days, and 6.0 days respectively. The most commonly affected organ systems were the central nervous system (79, 33.2%) and respiratory system (55, 23.1%). Mechanical ventilation and admission after cardiopulmonary resuscitation (p < 0.001) were independent predictors of mortality. Infectious causes of illnesses were the leading causes of admission and death in the PICU.

Conclusion: The mortality rate of our PICU was 21.1 %. In this study, post-cardiopulmonary resuscitation admission and use of mechanical ventilation were statistically significant predictors of mortality indicating the need for well equipping and staffing the PICU to improve the outcome of such critically sick patients.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214737PMC
http://dx.doi.org/10.4314/ejhs.v32i3.4DOI Listing

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