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Exploration of metastasis-related signatures in osteosarcoma based on tumor microenvironment by integrated bioinformatic analysis.
Heliyon
January 2025
Center for Plastic & Reconstructive Surgery, Department of Orthopedics, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou, Zhejiang, 310014, China.
Background: The present study aims to explore the metastasis-related signatures in connection with tumor microenvironment (TME), revealing new molecular targets promising in improving osteosarcoma (OS) patients' outcomes.
Methods: The high-throughput sequencing data was downloaded from the TARGET database and performed the ESTIMATE algorithm. Metastasis-related information was obtained from the GSE21257 dataset.
An optimized irrigation water quality index for evaluating surface water sustainability status of an agricultural watershed.
Water Environ Res
January 2025
Soil, Water and Environmental Engineering Department, Jomo Kenyatta University of Agriculture and Technology (JKUAT), Nairobi, Kenya.
Maintaining good water quality is essential for drinking and agriculture. High water quality is crucial for irrigation to boost agricultural productivity and ensure sustainable water resource management. This study used in-depth physical and chemical analysis of water samples to evaluate the Kakia-Esamburmbur watershed's irrigation water sustainability.
View Article and Find Full Text PDFThe Dyson equalizer: adaptive noise stabilization for low-rank signal detection and recovery.
Inf inference
March 2025
Program in Applied Mathematics, Yale University, New Haven, CT 06520, US.
Detecting and recovering a low-rank signal in a noisy data matrix is a fundamental task in data analysis. Typically, this task is addressed by inspecting and manipulating the spectrum of the observed data, e.g.
View Article and Find Full Text PDFHighly Efficient Degradation of Bisphenol A by Peroxymonosulfate Activation Using Bamboo Kraft Lignin Single-Atom Catalyst.
Small
January 2025
Key Lab of Bamboo and Rattan Science & Technology, International Center for Bamboo and Rattan, Beijing, 100102, P. R. China.
A nitrogen-coordinated Fe single-atom catalyst (SA Fe-N/C) is synthesized using a homogeneous ethanol-based dissolution system with bamboo kraft lignin serving as the carbon source. Uniformly dispersed Fe atoms with an interatomic distance of less than 2 Å throughout the SA Fe-N/C structure are revealed through X-ray absorption spectral analysis and HAADF-STEM images, which possessed a high Fe loading of 2.69%.
View Article and Find Full Text PDFCommentary: Why do many cell biology papers contain fundamental bioenergetic errors?
Biochim Biophys Acta Bioenerg
January 2025
Buck Institute for Research on Aging, Novato, CA, United States of America. Electronic address:
To professional bioenergeticists, the thermodynamic and kinetic constraints on mitochondrial function are self-evident. It is therefore profoundly concerning that high-profile cell biology papers continue to appear containing fundamental bioenergetic errors that appear to have evaded the scrutiny of the principal investigator, co-authors, editors and, apparently, at least some of the referees. The problem is not new, and seems to stem from a perception that bioenergetics is a 'difficult' subject, both at undergraduate level, if it is taught in any depth, and in research, where cell biologists are faced with biophysical concepts such as protonmotive force, ion flux, redox potential and Gibbs free energy.
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