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Post-myocardial Infarction Heart Failure: A Review on Management of Drug Therapies. | LitMetric

Post-myocardial Infarction Heart Failure: A Review on Management of Drug Therapies.

Cureus

Consultant Intervention Cardiologist, Sahara Hospital, Lucknow, IND.

Published: June 2022

AI Article Synopsis

  • After a heart attack (myocardial infarction), patients are more likely to develop heart failure, especially those with left ventricular systolic dysfunction.
  • Clinical trials have shown that using neuro-hormonal inhibitors can significantly enhance survival rates and lower the chances of further heart issues.
  • The article reviews existing drug treatments for patients following a heart attack, focusing on those with or without complications like heart failure.

Article Abstract

After myocardial infarction (MI), patients are at a greater risk of heart failure. Post-MI patients with left ventricular systolic dysfunction have a higher risk of mortality or morbidity. Strong and compelling data from randomized trials have demonstrated that drug therapies intended for preventing post-MI remodeling with neuro-hormonal inhibitors can considerably improve short- and long-term outcomes, including death, reinfarction, and worsening heart failure. This article aims at summarizing clinical data on established pharmacological therapies in treating post-MI patients with or without left ventricular systolic dysfunction (LVSD), and with or without signs and symptoms of heart failure.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264286PMC
http://dx.doi.org/10.7759/cureus.25745DOI Listing

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