AI Article Synopsis
- Antibiotic abuse poses a serious global health threat, highlighting the need for eco-friendly detection methods.
- A lead-free CsZnCl perovskite nanocrystals probe was developed to effectively sense norfloxacin (NOR) using a modified reprecipitation method.
- The probe demonstrated strong blue emission and high sensitivity to NOR, with a detection range of 0.2 to 50.0 μM and a low limit of detection, making it suitable for biochemical applications.
Article Abstract
The abuse of antibiotics would seriously affect human health and has become of worldwide critical concern, thus it is urgent to develop an environmentally friendly and nontoxic fluorescent probe for antibiotics sensing. In this work, a lead-free CsZnCl perovskite nanocrystals (PNCs) probe was fabricated for sensing norfloxacin (NOR) employing a modified ligand-assisted reprecipitation method. The prepared CsZnCl PNCs probe had strong blue emission around 440 nm, and the characteristics of PNCs were systematically characterized by X-ray photoelectric spectroscopy (XPS), Fourier transforms infrared spectroscopy (FTIR), transmission electron microscope (TEM) and powder X-ray diffraction (XRD). The results revealed that the fluorescence intensity of the CsZnCl PNCs was significantly enhanced after the introduction of norfloxacin. The CsZnCl PNCs can be used as a fluorescent probe to selectively and sensitively detect norfloxacin in the concentration range from 0.2 to 50.0 μM, with a correlation coefficient (R) of 0.9954 and the limit of detection (LOD, 3σ) of 0.1499 µM. The preparation and application of a lead-free perovskite fluorescent probe for norfloxacin would promote the application of perovskite fluorescent probes in biochemical assays.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.saa.2022.121568 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Conjugated Microporous Polymer-Based Fluorescent Probe for Selective Detection of Nitro-explosives and Metal Nitrates.
ACS Appl Mater Interfaces
January 2025
School of Chemistry & Chemical Engineering, Henan University of Science and Technology, Luoyang, Henan 471023, People's Republic of China.
The sensitive and selective identification of nitroaromatic explosives and industrially ubiquitous nitrates, which are harmful to the environment, is crucial from the viewpoints of security and environmental remediation. New multifunctional fluorescent porous materials that can sense nitro-explosives and nitrates are under continuous development. To this end, this study synthesizes 3,10,15-/-3,10,16-tribromotrinaphtho[3.
View Article and Find Full Text PDFSingle-Cell Calcium Imaging for Studying the Activation of Calcium Ion Channels.
J Vis Exp
December 2024
School of Life Science, Beijing University of Chinese Medicine;
Single cell Ca imaging is essential for the study of Ca channels activated by various stimulations like temperature, voltage, native compound and chemicals et al. It primarily relies on microscopy imaging technology and the related Ca indicator Fura-2/AM (AM is the abbreviation for Acetoxymethyl ester). Inside the cells, Fura-2/AM is hydrolyzed by esterases into Fura-2, which can reversibly bind with free cytoplasmic Ca.
View Article and Find Full Text PDFCarbon dot-based fluorescent sensors for pharmaceutical detection: Current innovations, challenges, and future prospects.
Heliyon
December 2024
Department of Physics, Khalifa University of Science and Technology, Abu Dhabi, 127788, United Arab Emirates.
Environmental contamination by pharmaceuticals has become a matter of concern as they are released in sewage systems at trace levels, thus impacting biological systems. Increasing concerns about the low-level occurrence of pharmaceuticals in the environment demands sensitive and selective monitoring. Owing to their high sensitivity and specificity carbon dots (CDs) have emerged as suitable fluorescent sensors.
View Article and Find Full Text PDFBT-DNBS: a novel cyanine-based turn-on fluorescent probe with large Stokes shift for sensitive and selective detection of biothiols in live-cell imaging.
RSC Adv
January 2025
Division of Materials Science, Faculty of Environmental Earth Science, Hokkaido University Japan.
Detecting biothiols like glutathione (GSH), homocysteine (Hcy), and cysteine (Cys) is key to understanding their roles in health and disease. We developed BT-DNBS, a cyanine-based turn-on fluorescent probe with a dinitrobenzenesulfonyl (DNBS) quencher group. Upon biothiol interaction, the quencher is cleaved, restoring fluorescence.
View Article and Find Full Text PDFA turn-on fluorescent probe containing a β-ketoester moiety for the selective detection of intracellular hydrazine.
RSC Adv
January 2025
Laboratory of Bioorganic & Natural Products Chemistry, Kobe Pharmaceutical University 4-19-1, Motoyamakita, Higashinada Kobe Hyogo 658-8558 Japan
Fluorogenic probes containing the β-ketoester structure were developed for selective hydrazine detection. The probe equipped with a cyclopropane moiety, having reduced steric hindrance, showed a higher reaction rate than its dimethyl counterpart. In live cell imaging, the probe detects intracellular hydrazine with minimal cytotoxicity.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!