Mobile edge computing (MEC) has become an indispensable part of the era of the intelligent manufacturing industry 4.0. In the smart city, computation-intensive tasks can be offloaded to the MEC server or the central cloud server for execution. However, the privacy disclosure issue may arise when the raw data is migrated to other MEC servers or the central cloud server. Since federated learning has the characteristics of protecting the privacy and improving training performance, it is introduced to solve the issue. In this article, we formulate the joint optimization problem of task offloading and resource allocation to minimize the energy consumption of all Internet of Things (IoT) devices subject to delay threshold and limited resources. A two-timescale federated deep reinforcement learning algorithm based on Deep Deterministic Policy Gradient (DDPG) framework (FL-DDPG) is proposed. Simulation results show that the proposed algorithm can greatly reduce the energy consumption of all IoT devices.
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http://dx.doi.org/10.3390/s22134738 | DOI Listing |
Anal Methods
January 2025
Department of Chemistry, Universidade Federal de Santa Catarina, Florianópolis, SC, 88035-972, Brazil.
A new analytical method was developed for the determination of 14 multiclass emerging organic contaminants in surface waters using LC-MS, and Dispersive Liquid-Liquid Microextraction (DLLME) for extraction. Different Natural Deep Eutectic Solvents (NADESs) composed of terpenes and organic acids were tested as extraction solvents and characterized by Fourier Transform Infrared Spectroscopy (FTIR), Hydrogen Nuclear Magnetic Resonance Spectroscopy (H-NMR), Differential Scanning Calorimetry (DSC), Thermogravimetric Analysis (TGA), density, and viscosity, eliminating the need to use traditional chlorinated solvents. NADES produced with butyric acid and thymol showed the best results and was selected for application for the first time in the extraction of emerging organic contaminants of different classes in water samples.
View Article and Find Full Text PDFNat Genet
January 2025
Institute of Molecular Oncology, Philipps-University, Marburg, Germany.
The mutational landscape of TP53, a tumor suppressor mutated in about half of all cancers, includes over 2,000 known missense mutations. To fully leverage TP53 mutation status for personalized medicine, a thorough understanding of the functional diversity of these mutations is essential. We conducted a deep mutational scan using saturation genome editing with CRISPR-mediated homology-directed repair to engineer 9,225 TP53 variants in cancer cells.
View Article and Find Full Text PDFSensors (Basel)
December 2024
Postgraduate Program in Biotechnology, Parnaíba Delta Federal University, Parnaíba 64202-020, Brazil.
Human Pose Estimation (HPE) is a computer vision application that utilizes deep learning techniques to precisely locate Key Joint Points (KJPs), enabling the accurate description of a person's pose. HPE models can be extended to facilitate Range of Motion (ROM) assessment by leveraging patient photographs. This study aims to evaluate and compare the performance of HPE models for assessing upper limbs ROM.
View Article and Find Full Text PDFPlants (Basel)
December 2024
Centro Nacional de Excelencia para la Industria de la Madera (CENAMAD)-ANID BASAL FB210015, Pontificia Universidad Católica de Chile, Santiago 7820436, Chile.
D. Don is the most widely planted forest species in Chile, making it crucial to understand carbon pools in adult plantations. This study aimed to evaluate the effect of soil type and site productivity on the total carbon stock in adult radiata pine plantations, considering sites with contrasting water and nutrient availability.
View Article and Find Full Text PDFInt J Mol Sci
December 2024
Artificial Intelligence Research Center, Institute of Information Technologies, Mathematics and Mechanics, Lobachevsky State University, 603022 Nizhny Novgorod, Russia.
Yakutia is one of the coldest permanently inhabited regions in the world, characterized by a subarctic climate with average January temperatures near -40 °C and the minimum below -60 °C. Recently, we demonstrated accelerated epigenetic aging of the Yakutian population in comparison to their Central Russian counterparts, residing in a considerably milder climate. In this paper, we analyzed these cohorts from the inflammaging perspective and addressed two hypotheses: a mismatch in the immunological profiles and accelerated inflammatory aging in Yakuts.
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