Paulownia is a fast-growing tree that produces a huge mass of leaves as waste that can be used as a feed source for ruminants. The previous study showed that phenolic compounds were the most active biological substances in leaves, which affected the ruminal parameters and methane concentration. However, there are no scientific reports on the leaves extract (PLE) containing phenolic compounds for their mode of action in the rumen. Phenolics constituted the main group of bioactive compounds in PLE (84.4 mg/g dry matter). PLE lowered the concentration of ammonia, modulated the VFA profile in the ruminal fluid, and decreased methane production. The PLE caused a significant reduction of in vitro dry matter degradability, reduced the number of methanogens and protozoa, and affected selected bacteria populations. PLE had a promising effect on the fatty acid profile in the ruminal fluid. as a new dietary component or its extract as a feed additive may be used to mitigate ruminal methanogenesis, resulting in environmental protection and reducing ruminal biohydrogenation, improving milk and meat quality.
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http://dx.doi.org/10.3390/molecules27134288 | DOI Listing |
Sci Rep
January 2025
D. Y. Patil Agriculture and Technical University, Talsande, Maharashtra, India.
Indian agriculture is vital sector in the country's economy, providing employment and sustenance to millions of farmers. However, Plant diseases are a serious risk to crop yields and farmers' livelihoods. Traditional plant disease diagnosis methods rely heavily on human expertise, which can lead to inaccuracies due to the invisible nature of early disease symptoms and the labor-intensive process, making them inefficient for large-scale agricultural management.
View Article and Find Full Text PDFAm J Chin Med
January 2025
School of Pharmacy, Nantong University, 9 Seyuan Road, Nantong 226019, P. R. China.
Ginkgolic acids (GAs) are distinctive secondary metabolites of () primarily found in its leaves and seeds, with the highest concentration located in the exotesta. GAs are classified as long-chain phenolic compounds, and exhibit structural similarities to lignoceric acid. Their structural diversity arises from variations in the length of side chains and their number of double bonds, resulting in six distinct forms within extracts (GBE).
View Article and Find Full Text PDFBiomed Mater
January 2025
Physics and Applied Mathematics, Pakistan Institute of Engineering and applied Sciences, P.O. Box Nilore, Islamabad., Islamabad, Islamabad, 44000, PAKISTAN.
Ficus Carica extract (FC) is a natural herb that has received a lot of interest in cancer treatment due to its potential anticancer activities against various malignancies. However, due to FC's low bioavailability and low solubility, its clinical use as an anti-cancer medicine is constrained. The current study aimed to prepare FC-loaded PLGA nanoparticles (NPs) for cancer treatment.
View Article and Find Full Text PDFPLoS One
January 2025
Faculty of Health and Medicine, Lancaster University, Lancaster, United Kingdom.
Background: Strokes are becoming more common, and with improving survival rates, the prevalence of stroke survivors has increased. Almost half of chronic stroke survivors are cognitively impaired, and healthcare services are struggling to manage these patients, leaving some feeling "abandoned". Several systematic reviews have investigated the effect of physical exercise and cognition-orientated interventions on post-stroke cognitive impairment, and have produced conflicting findings, making it difficult for clinicians and guideline producers to make evidence-based decisions.
View Article and Find Full Text PDFBraz J Microbiol
January 2025
Innovation and Drug Discovery, Sava Healthcare Limited, Research Center, MIDC, Block D1, Plot No. 17/6, Chinchwad, Pune, 411019, India.
Plant parts such as roots, bark, leaves, flowers, and fruits that hold ethnopharmacological significance are naturally prone to microbial contamination, influenced by environmental factors like moisture and humidity. This study focuses on assessing the microbial load in the raw material of Tribulus terrestris (TT). The primary bacterium isolated from the pulverized raw material was identified as Bacillus haynesii through 16S rRNA sequencing.
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