Enhanced Muscle Fibers of by Autologous Nucleic Acid Vaccine.

is a fish species with high economic value due to its delicious meat, high protein content, and rich fatty acid nutrition. It has become a high-economic fish in southern parts of China and some other Southeast Asian countries. In this study, the nucleic acid vaccine was constructed and used to immunize . The results from body length and weight measurements indicated the nucleic acid vaccine promoted growth performance by increasing muscle fiber size. The results from RT-qPCR analysis showed that nucleic acid vaccine upregulated the expression of , and mRNA, downregulated the expression of and mRNA. This preliminary study is the first report that explored the role of in and showed positive effects of autologous nucleic acid vaccine on the muscle growth of . Further experiments with increased numbers of animals and different doses are needed for its application to aquaculture production.