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Biological Activity of Biomarkers Associated With Metastasis in Osteosarcoma Cell Lines.
Cancer Med
March 2025
Universidad Autónoma del Estado de Morelos, Facultad de Medicina, Cuernavaca, Morelos, Mexico.
Introduction: Osteosarcoma, a highly aggressive bone cancer primarily affecting children and young adults, remains a significant challenge in clinical oncology. Metastasis stands as the primary cause of mortality in osteosarcoma patients. However, the mechanisms driving this process remain incompletely understood.
View Article and Find Full Text PDFRecurrent falls as the presentations of Gitelman syndrome in an octogenarian.
Aging (Albany NY)
March 2025
Division of Nephrology, Department of Internal Medicine, National Defense Medical Center, Taipei 104, Taiwan.
Gitelman syndrome (GS) is the most common hereditary renal tubular disorder, with a higher carrier frequency among Asians often overlooked in older adults. Electrolyte imbalances, such as those seen in GS, are crucial considerations for older adults experiencing recurrent falls. We described an 83-year-old diabetic female on metformin, who was admitted due to recurrent falls with the preceding dizziness and palpitations when standing.
View Article and Find Full Text PDFAluminum phosphide (AlP) poisoning typically has a poor prognosis, but this case report from Nepal demonstrated that prompt hospitalization, aggressive supportive care, including gastric lavage with coconut oil, and careful management of metabolic acidosis can lead to successful patient recovery.
View Article and Find Full Text PDFAn Unusual Cause of Hypokalemia to Consider.
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Department of Nephrology, Hospital Universitario La Paz, Madrid 28046, Spain.
Apparent mineralocorticoid excess syndrome is a rare disorder that can be acquired through inhibition of the enzyme 11 β-hydroxysteroid dehydrogenase type 2 by various substances such as bile acids. We report the case of a 61-year-old woman presenting with painless jaundice. Computed tomography demonstrated a pulmonary as well as a pancreatic tumor, with multiple metastases and dilated bile ducts.
View Article and Find Full Text PDFStructure-Properties Correlations in Novel Copoly(urethane-imide) Films Selectively Destructed Under Thermolysis and Hydrolysis in Alkaline Media.
Polymers (Basel)
January 2025
A.V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences, 29 Leninsky Prospekt, 119991 Moscow, Russia.
The paper describes changes in the structure, morphology, mechanical and thermal properties of porous film samples of poly(4,4'-oxidiphenylene)pyromellitimide prepared as a result of selective destruction of urethane blocks in copolymers composed of pyromellitimide blocks and polyurethane blocks. The initial samples of the new composition of statistical copoly(urethane-imide)s (CoPUIs) were prepared via polycondensation methods using pyromellitic dianhydride (PMDA), 4,4'-oxidyaniline (ODA), 2,4-toluylenediisocyanate (TDI), as well as polycaprolactone (PCL) and poly(1,6-hexanediol/neopentylglycol-alt-adipic acid) (ALT) as monomers. The molar ratio of imide and polyurethane blocks in CoPUI was 10:1.
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