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Background: Behaviour change interventions targeting social norms are burgeoning, but researchers have little guidance on what they look like, and which components affect behaviour change. The Reduction in Anaemia through Normative Innovations (RANI) project designed an intervention to increase iron folic acid (IFA) consumption in Odisha, India.
Objective: This paper examines the effect of the intervention at midline to understand which components of the RANI intervention affect uptake.
Methods: Using a cluster randomised controlled design, we collected baseline data and midline data 6 months later from women of reproductive age in the control and treatment arms (n=3800) in Angul, Odisha, India. Using nested models, we analysed data from three different intervention components, monthly community-based testing for anaemia, participatory group education sessions, and videos, to determine the extent to which exposure to each of these components accounted for the overall intervention effect on haemoglobin and self-reported IFA use.
Results: Overall, residing in a treatment as opposed to control village had little effect on midline haemoglobin, but increased the odds of taking supplements by 17 times. Exposure to each of the intervention components had a dose-response relationship with self-reported IFA use. These components, separately and together, accounted for most of the overall effect of treatment assignment on IFA use.
Conclusions: All intervention components increased iron supplement use to differing degrees of magnitude. It appears that a social norms-based approach can result in improving IFA uptake, though improvements in haemoglobin counts were not yet discernible.
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http://dx.doi.org/10.1136/bmjopen-2021-053152 | DOI Listing |
J Int Med Res
December 2024
Department of Hematology, The First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui, China.
Objective: Mobilization and collection of peripheral blood stem cells (PBSCs) are time-intensive and costly. Excessive apheresis sessions can cause physical discomfort for donors and increase the costs associated with collection. Therefore, it is essential to identify key predictive factors for successful harvests to minimize the need for multiple apheresis procedures.
View Article and Find Full Text PDFJ Infect Dis
December 2024
Biostatistics Research Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Background: The robustness and persistence of vaccine antigen-induced antibodies are often used as proxy indicators of vaccine efficacy, but immune responses to vaccine vectors are typically less well-defined. Our study considered the kinetics of immunoglobulin (IgG) responses against the vector (vesicular stomatitis Indiana virus [VSIV]) nucleoprotein (N) and the inserted antigen (Ebola virus [EBOV]) glycoprotein (GP1,2) components of the rVSVΔG-ZEBOV-GP (rVSV-ZEBOV) vaccine and evaluated their use as biomarkers to confirm self-reported vaccination status.
Methods: From the Partnership for Research on Ebola Virus in Liberia (PREVAIL) I clinical trial (NCT02344407), we randomly selected 212 participants who received rVSV-ZEBOV (n=107) or placebo (n=105).
Vopr Kurortol Fizioter Lech Fiz Kult
December 2024
Federal Scientific and Clinical Center of Medical Rehabilitation and Balneology of the Federal Medical and Biological agency of Russia, Moscow, Russia.
Unlabelled: Chronic kidney disease (CKD) is a global health problem, CKD is widespread in the world, on average it is detected in 10-13% of the adult population. Sedentary patients with CKD on dialysis have a higher risk of mortality. Despite the significant association of physical function with mortality in patients with CKD, physical function is not routinely assessed and exercise is not a component of the routine management of patients with CKD on dialysis.
View Article and Find Full Text PDFVopr Kurortol Fizioter Lech Fiz Kult
December 2024
National Medical Research Center for Rehabilitation and Balneology, Moscow, Russia.
Unlabelled: Lymphedema is a chronic disabling disease that affects 250 million people worldwide. To this date, it has been proven that treatment of this category of patients should be truly integrated - combining surgical, therapeutic methods and recovery procedures.
Objective: To study the influence of intermittent pneumatic compression (IPC) on microvasculature in patients with lymphedema of the lower extremities.
Vopr Kurortol Fizioter Lech Fiz Kult
December 2024
S.I. Spasokukotsky Moscow Centre for Research and Practice in Medical Rehabilitation, Restorative and Sports Medicine of the Moscow Healthcare Department, Moscow, Russia.
Unlabelled: Essential arterial hypertension (EAH) is a chronic non-communicable disease (CNCD), that develops in parallel with other pathologies of the CNCD group, the presence of which is promoted by hypodynamia with consequent disturbance of aerobic energy supply processes. These disorders include, in particular, degenerative-dystrophic processes of the locomotor system, comprising of the cervical spine. In turn, development of these processes can additionally worsen hemodynamics with disturbance of the oxygen transfer processes.
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