AI Article Synopsis
- The fixed-combination drug latanoprost/timolol is one of the most effective treatments for open-angle glaucoma, especially crucial for patients with normal-tension glaucoma.
- All seven patients studied in a 10-year follow-up tolerated the medication well, with their quality of life largely maintained.
- While one patient experienced mild symptoms of dry eye and another showed slight disease progression, overall, latanoprost/timolol is deemed a safe and effective long-term treatment option for normal-tension glaucoma.
Article Abstract
The most well-studied and widely prescribed fixed-combination drug for open-angle glaucoma is latanoprost/timolol. Its significant hypotensive effect is especially important in challenging cases, among which are patients with normal-tension glaucoma. With long life expectancy and the constant need for treatment, requirements are high for both the effectiveness of the drug and its tolerability. This paper presents a follow-up of 7 patients with normal-tension glaucoma who have been using the fixed combination of latanoprost/timolol for 10 years. All patients showed very good tolerability to the drug and their quality of life was preserved. A moderate rate of disease progression according to static perimetry was noted in one case. A mild degree of dry eye syndrome according to the OSDI questionnaire and an objective assessment of the state of the ocular surface was observed in one patient. The latanoprost/timolol fixed combination is a well-tolerated, highly effective and safe long-term treatment choice for normal-tension glaucoma.
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| http://dx.doi.org/10.17116/oftalma202213803182 | DOI Listing |
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