AI Article Synopsis
- LIN-11 is an important transcription factor involved in the development of the vulva, uterus, and neurons.
- Researchers discovered a reference allele that features a significant 15,900 base pair deletion impacting two additional protein-coding genes, ZC247.1 and ZC247.2.
- A commonly used allele has a smaller 288 base pair deletion located in an intron, which modifies the splice acceptor site.
Article Abstract
The LIM homeodomain transcription factor LIN-11 is a key regulator of vulva, uterine, and neuron development in Multiple alleles of are available, but none had been sequenced. We found that the reference allele, is a 15900 bp deletion that also affects two other protein-coding genes, ZC247.1 and ZC247.2. The frequently used allele is a 288bp deletion located in an intron and affecting the splice acceptor site.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9253893 | PMC |
| http://dx.doi.org/10.17912/micropub.biology.000589 | DOI Listing |
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