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Updates in therapeutic drug monitoring in inflammatory bowel disease. | LitMetric

Updates in therapeutic drug monitoring in inflammatory bowel disease.

World J Gastroenterol

Department of Gastroenterology and Hepatology, Atrium Health, Charlotte, NC 28203, United States.

Published: June 2022

Biologics and immunomodulators (IMM) are generally considered the most effective therapies for the treatment of ulcerative colitis and Crohn's disease. However, despite the efficacy of these therapies, many patients either have a primary lack of response or a secondary loss of response to these medications. Therapeutic drug monitoring (TDM) is a systematic approach to managing such patients. In this review, we summarize the latest data on TDM, including reactive and proactive TDM, in patients with inflammatory bowel disease on biologics and/or IMM.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9185221PMC
http://dx.doi.org/10.3748/wjg.v28.i21.2282DOI Listing

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