Catecholamine-resistant postoperative vasoplegic syndrome (PVS) lacks effective treatment modalities. Synthetic angiotensin II was recently approved for the treatment of vasodilatory shock; however, its use in PVS is not well described. We report outcomes in six patients receiving angiotensin II for the treatment of isolated PVS. All patients achieved their MAP goal and the majority showed improvement in lactate and background catecholamine dose; however, variables of perfusion changed discordantly. Three of six patients survived to hospital discharge.
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http://dx.doi.org/10.4103/aca.aca_98_21 | DOI Listing |
Anaesthesiologie
January 2025
Klinik für Herz‑, Thorax‑, Transplantations- und Gefäßchirurgie, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland.
Hemodynamic treatment is a core task in the intensive medical care of cardiac surgery patients. The patient's underlying disease, the type of surgical procedure and the patient's individual characteristics play key roles in the selection of the treatment regimen. The basis of any targeted hemodynamic treatment is the differential diagnosis of the underlying pathological disorder.
View Article and Find Full Text PDFMed Intensiva (Engl Ed)
December 2024
Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
The most used vasopressors in critically ill patients are exogenous catecholamines, mainly norepinephrine. Their use can be associated with serious adverse events and even increased mortality, especially if administered at high doses. In recent years, the addition of vasopressin has been proposed to counteract the deleterious effects of high doses of catecholamines (decatecholaminization) with the intention of improving the prognosis of these patients.
View Article and Find Full Text PDFJ Cardiothorac Vasc Anesth
December 2024
Anaesthetics Department, Royal Sussex County Hospital, University Hospitals Sussex, United Kingdom.
Arch Peru Cardiol Cir Cardiovasc
June 2024
Hospital Regional Primero de Octubre ISSSTE, Mexico City, Mexico. Hospital Regional Primero de Octubre ISSSTE Mexico City Mexico.
Rev Fac Cien Med Univ Nac Cordoba
June 2024
Universidad de Buenos Aires.
Introduction: Cardiovascular surgery risk prediction models are widely applied in medical practice. However, they have been criticized for their low methodological quality and scarce external validation. An additional limitation added in Latin America is that most of these models have been developed in the United States or Europe, which present marked geographical differences.
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