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Dynamics of affect modulation in neurodevelopmental disorders (DynAMoND) - study design of a prospective cohort study.
Int J Bipolar Disord
December 2024
Department for Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt-Goethe University, Frankfurt am Main, Germany.
Background: Attention-deficit/hyperactivity disorder (ADHD) is a common neuro-developmental disorder that often persists into adulthood. Moreover, it is frequently accompanied by bipolar disorder (BD) as well as borderline personality disorder (BPD). It is unclear whether these disorders share underlying pathomechanisms, given that all three are characterized by alterations in affective states, either long or short-term.
View Article and Find Full Text PDFNutrient loading as a key cause of short- and long-term anthropogenic ecological degradation of the Salton Sea.
Sci Rep
December 2024
Department of Earth and Planetary Sciences, University of California, Riverside, CA, 92521, USA.
The Salton Sea (SS), California's largest inland lake at 816 square kilometers, formed in 1905 from a levee breach in an area historically characterized by natural wet-dry cycles as Lake Cahuilla. Despite more than a century of untreated agricultural drainage inputs, there has not been a systematic assessment of nutrient loading, cycling, and associated ecological impacts at this iconic waterbody. The lake is now experiencing unprecedented degradation, particularly following the 2003 Quantification Settlement Agreement-the largest agricultural-to-urban water transfer in the United States.
View Article and Find Full Text PDFLoss values of style transfer from UBM to AS-OCT images for plateau iris classification.
Sci Rep
December 2024
Sirindhorn International Institute of Technology, Thammasat University, Pathum Thani, Thailand.
Ultrasound biomicroscopy (UBM) is the standard for diagnosing plateau iris, but its limited accessibility in routine clinical settings presents challenges. While anterior segment optical coherence tomography (AS-OCT) is more convenient, its effectiveness in detecting plateau iris is limited. Previous research has demonstrated that combining UBM and AS-OCT image pairs through neural style transfer has improved classification accuracy.
View Article and Find Full Text PDFOptimized fuzzy logic and sliding mode control for stability and disturbance rejection in rotary inverted pendulum.
Sci Rep
December 2024
Innovative Global Program, Shibaura Institute of Technology, Tokyo, 135-8548, Japan.
This paper presents a novel and comprehensive control framework for the Rotary Inverted Pendulum (RIP), focusing on a hybrid control strategy that addresses the limitations of conventional methods in nonlinear and complex systems. The proposed controller synergistically combines an Optimized Fuzzy Logic Controller (OFLC) with Sliding Mode Control (SMC), leveraging the strengths of both techniques to achieve superior performance. The integration of Particle Swarm Optimization (PSO) into the OFLC significantly enhances its adaptability and precision, while the SMC law provides robust disturbance rejection and system stability.
View Article and Find Full Text PDFAssociations between ABO, FUT2 and chronic pancreatitis: A comprehensive meta-analysis of multiple cohorts and public biobanks.
Pancreatology
December 2024
Department of Gastroenterology, National Clinical Research Center for Digestive Diseases, Changhai Hospital, Naval Medical University, Shanghai, 200433, China. Electronic address:
Objectives: Associations of ABO blood group specifying transferases A/B (ABO) and fucosyltransferase 2 (FUT2) with CP remain inconclusive. We aimed to comprehensively investigate the associations by Chinese sequencing cohorts and external cohorts.
Methods: First, we analyzed the distributions of ABO blood groups and FUT2 status, along with lead single nucleotide polymorphisms (SNPs) at ABO (rs8176693 C/T) and FUT2 (rs632111 A/G) gene loci in Chinese low-coverage whole-genome sequencing discovery cohort.
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