Background: Medial ulnar collateral ligament (UCL) repair utilization is increasing in recent years, bolstered by shorter rehabilitation and satisfactory clinical outcomes. Although previous literature has illustrated the importance of tunnel position on restoring graft isometry in reconstruction, there remains a paucity of literature guiding anchor placement in UCL repair. The purpose of this study is to design a 3-dimensional (3D) elbow model to understand the effect of anchor location on UCL repair isometry.
Methods: A 3D computer model of an elbow joint was created using computed tomographic and magnetic resonance imaging MRI scans from a single patient. The humeral and ulnar attachments of the UCL were plotted using 3 methodologies: (1) geometric cloud mapping and (2) quantitative measurements from the anatomic studies by Camp et al and (3) Frangiamore et al. A 3.5-mm-diameter clockface was placed on each attachment site, which allowed for simulation of 12 distinct 1.75-mm deviations in anchor position. The 3 models were ranged through 0°-120° at 10° increments, and the 3D distances were measured between the ligament centroids. The humeral and ulnar anchors were sequentially repositioned around the clockfaces, and construct lengths were again measured to evaluate changes in isometry. A paired Student t test was performed to determine if there was a significant difference in isometry between the humeral and ulnar anchor deviations.
Results: Using method 1, the UCL repair length at 90° of elbow flexion was 26.8 mm. This construct underwent 13.6 mm of total excursion for a 46.4% change in length throughout its arc of motion. Method 2 produced a 19.3-mm construct that underwent 0.8 mm of excursion for a 3.9% length change throughout the arc. Method 3 produced a 24.5-mm construct that underwent 2.3 mm of excursion for a 9.4% length change. Identifying ligament footprints using the quantitative anatomic measurements from Camp et al and Frangiamore et al improved construct isometry through 120° of flexion (length changes of 3.9% and 9.4%, respectively) when compared to using the geometric cloud technique alone (46.4% length change). Humeral anchor deviations produced a significant increase in repair construct excursion compared with ulnar anchor deviations (P < .001).
Conclusion: When performing UCL repair, small deviations in humeral anchor position may significantly influence ligament repair isometry. Using quantitative anatomic data may help identify anchor positions with improved repair isometry. Particularly when addressing detachments of the humeral footprint, surgeons should be critical of the humeral anchor position in order to restore native anatomy and optimal biomechanics.
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http://dx.doi.org/10.1016/j.jse.2022.05.028 | DOI Listing |
Alzheimers Dement
December 2024
Mayo Clinic, Rochester, MN, USA
Background: Phase four of the Alzheimer’s Disease Neuroimaging Initiative (ADNI4) began in 2023. This time‐period corresponded to MRI vendors introducing product sequences with compressed sensing (CS), cross‐vendor adoption of arterial spin‐labelling (ASL) and multi‐band slice excitation, and hardware improvements (head‐coils, increased gradient amplitudes). These advances enabled the acquisition of new imaging measures and reduced scan times.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Dementia Research Centre, UCL Queen Square Institute of Neurology, London, UK
Background: With an aging population, it is essential to identify subtle features of brain pathology – both neurodegenerative and vascular – at an early stage, which may predict risk of future decline. We used diffusion MRI (dMRI) to assess grey matter cortical microstructure and investigate associations with 1) Alzheimer’s disease (AD) pathology and 2) mid/late‐life vascular risk (as measured by blood pressure (BP)).
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Alzheimers Dement
December 2024
Dementia Research Centre, UCL Queen Square Institute of Neurology, London, United Kingdom
Background: Understanding when Aβ positive cognitively normal individuals develop tau pathology has important implications for treatment with anti‐Aβ therapies. We employed a changepoint regression approach to estimate time from Aβ‐PET positivity to regionally elevated tau‐PET in a population‐based cohort of primarily cognitively unimpaired individuals.
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Alzheimers Dement
December 2024
Dementia Research Centre, UCL Queen Square Institute of Neurology, London, UK
Background: Cerebral Aβ accumulates decades before symptom onset in AD. Sampled iterative local approximation (SILA, Betthauser et al. 2022) is a technique for estimating time from Aβ positivity (Aβ+) using Aβ‐PET.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Mayo Clinic, Rochester, MN, USA
Background: Phase four of the Alzheimer’s Disease Neuroimaging Initiative (ADNI4) began in 2023. This time‐period corresponded to MRI vendors introducing product sequences with compressed sensing (CS), cross‐vendor adoption of arterial spin‐labelling (ASL) and multi‐band slice excitation, and hardware improvements (head‐coils, increased gradient amplitudes). These advances enabled the acquisition of new imaging measures and reduced scan times.
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