Microscopy image analysis gives quantitative support for enhancing the characterizations of various diseases, including breast cancer, lung cancer, and brain tumors. As a result, it is crucial in computer-assisted diagnosis and prognosis. Understanding the biological principles underlying these dynamic image sequences often necessitates precise analysis and statistical quantification, a major discipline issue. Deep learning methods are increasingly used in bioimage processing as they grow rapidly. This research proposes novel biomedical microscopic image analysis techniques using deep learning architectures based on feature extraction and classification. Here, the input image has been taken as microscopic image, and it has been processed and analyzed for noise removal, edge smoothening, and normalization. The processed image has been extracted based on their features in microscopic image analysis using ConVol_NN architecture with AlexNet model. Then, the features have been classified using ensemble of Inception-ResNet and VGG-16 (EN_InResNet_VGG-16) architectures. The experimental results show various dataset analyses in terms of accuracy of 98%, precision of 90%, computational time of 79%, SNR of 89%, and MSE of 62%.
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http://dx.doi.org/10.1155/2022/3531308 | DOI Listing |
Adv Sci (Weinh)
January 2025
DP Technology, Beijing, 100080, China.
Powder X-ray diffraction (PXRD) is a prevalent technique in materials characterization. While the analysis of PXRD often requires extensive human manual intervention, and most automated method only achieved at coarse-grained level. The more difficult and important task of fine-grained crystal structure prediction from PXRD remains unaddressed.
View Article and Find Full Text PDFAdv Sci (Weinh)
January 2025
School of Pharmacy, Sungkyunkwan University, Suwon, 16419, Republic of Korea.
β-secretase (BACE1) is instrumental in amyloid-β (Aβ) production, with overexpression noted in Alzheimer's disease (AD) neuropathology. The interaction of Aβ with the receptor for advanced glycation endproducts (RAGE) facilitates cerebral uptake of Aβ and exacerbates its neurotoxicity and neuroinflammation, further augmenting BACE1 expression. Given the limitations of previous BACE1 inhibition efforts, the study explores reducing BACE1 expression to mitigate AD pathology.
View Article and Find Full Text PDFSci Rep
January 2025
North Carolina School of Science and Mathematics, Durham, NC, 27705, USA.
Mobile Ad Hoc Networks (MANETs) are increasingly replacing conventional communication systems due to their decentralized and dynamic nature. However, their wireless architecture makes them highly vulnerable to flooding attacks, which can disrupt communication, deplete energy resources, and degrade network performance. This study presents a novel hybrid deep learning approach integrating Convolutional Neural Networks (CNN) with Long Short-Term Memory (LSTM) and Gated Recurrent Unit (GRU) architectures to effectively detect and mitigate flooding attacks in MANETs.
View Article and Find Full Text PDFNPJ Digit Med
January 2025
Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Adaptive deep brain stimulation (DBS) provides individualized therapy for people with Parkinson's disease (PWP) by adjusting the stimulation in real-time using neural signals that reflect their motor state. Current algorithms, however, utilize condensed and manually selected neural features which may result in a less robust and biased therapy. In this study, we propose Neural-to-Gait Neural network (N2GNet), a novel deep learning-based regression model capable of tracking real-time gait performance from subthalamic nucleus local field potentials (STN LFPs).
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January 2025
College of Computer and Data Science, Minjiang University, Fuzhou, 350018, China.
This study presents a novel approach to identifying meters and their pointers in modern industrial scenarios using deep learning. We developed a neural network model that can detect gauges and one or more of their pointers on low-quality images. We use an encoder network, jump connections, and a modified Convolutional Block Attention Module (CBAM) to detect gauge panels and pointer keypoints in images.
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