Two new peptides named uniformides A and B ( and , respectively) were isolated from the cultured extracts of IFM0856 in the presence of mouse macrophage-like cell line J774.1, in modified Czapek-Dox medium. These compounds were not produced in a culture containing only but in one that also included J774.1. Compounds and showed high cytotoxicity against J774.1 and suppressed the production of nitric oxide, IL-6, and IL-1β by inhibiting the NF-κB pathway.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/acs.orglett.2c02092 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Corrrection to "Two Bioactive Compounds, Uniformides A and B, Isolated from a Culture of IFM0856 in the Presence of Animal Cells".
Org Lett
August 2022
Graduate School of Pharmaceutical Sciences, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8675, Japan.
Two Bioactive Compounds, Uniformides A and B, Isolated from a Culture of IFM0856 in the Presence of Animal Cells.
Org Lett
July 2022
Graduate School of Pharmaceutical Sciences, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8675, Japan.
Two new peptides named uniformides A and B ( and , respectively) were isolated from the cultured extracts of IFM0856 in the presence of mouse macrophage-like cell line J774.1, in modified Czapek-Dox medium. These compounds were not produced in a culture containing only but in one that also included J774.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!