AI Article Synopsis
- Proprioceptive feedback from skeletal muscles is crucial for motor control, but understanding the specific roles of muscle spindles and Golgi tendon organs has been challenging.
- Advances in molecular understanding of these sensory receptors provide genetic tools to differentiate their functional roles.
- These insights reveal a more complex regulation of coordinated motor output than previously thought.
Article Abstract
Proprioceptive feedback from skeletal muscle is an integral element of motor control, yet the precise physiological roles of muscle spindle (MS) and Golgi tendon organ (GTO) sensory receptors have remained difficult to disentangle due to technical limitations. New insights into the molecular basis of MS and GTO afferent subtypes offers genetic opportunities to further our understanding of the distinct functional features of these proprioceptor classes, while at the same time revealing additional layers of complexity in the regulation of coordinated motor output.
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| http://dx.doi.org/10.1016/j.conb.2022.102597 | DOI Listing |
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