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Dual Blood Purification with CytoSorb and oXiris in Managing Recurrent Septic Shock: A Case Report.
Am J Case Rep
January 2025
Department of Anesthesiology and Intensive Care, Legionowo Hospital, Military Institute of Medicine - National Research Institute, Warsaw, Poland.
BACKGROUND Extracorporeal blood purification strategies were recently developed as adjunctive treatments for sepsis. CytoSorb® is an approved medical device designed to reduce blood levels of inflammatory cytokines. The oXiris high-adsorption membrane filter is used in continuous hemofiltration adsorption.
View Article and Find Full Text PDFLung injury in myocardial infarction-associated cardiogenic shock supported by venoarterial extracorporeal membrane oxygenation: a scoping review.
BMC Cardiovasc Disord
January 2025
Department of Surgery, Division of Cardiac Surgery, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Background: Acute lung injury and acute respiratory failure are frequent complications of cardiogenic shock and are associated with increased morbidity and mortality. Even with increased use of temporary mechanical circulatory support, such as venoarterial extracorporeal membrane oxygenation (VA-ECMO), acute lung injury related to cardiogenic shock continues to have a determinantal effect on patient outcomes.
Objectives: To summarize potential mechanisms of acute lung injury described in patients with cardiogenic shock supported by VA-ECMO and determine current knowledge gaps.
Comparing clinical only and combined clinical laboratory models for ECPR outcomes in refractory cardiac arrest.
Sci Rep
January 2025
Department Emergency and Critical Care Medicine, Changhua Christian Hospital, Changhua, 50006, Taiwan.
Extracorporeal cardiopulmonary resuscitation (ECPR) improves survival for prolonged cardiac arrest (CA) but carries significant risks and costs due to ECMO. Previous predictive models have been complex, incorporating both clinical data and parameters obtained after CPR or ECMO initiation. This study aims to compare a simpler clinical-only model with a model that includes both clinical and pre-ECMO laboratory parameters, to refine patient selection and improve ECPR outcomes.
View Article and Find Full Text PDFDevelopment of a health equity tool in resuscitation sciences and application to current research in extracorporeal cardiopulmonary resuscitation for cardiac arrest.
Resuscitation
January 2025
Department of Emergency Services, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; Division of Emergency Medicine, Department of Medicine, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Background: Extracorporeal cardiopulmonary resuscitation (ECPR) is increasingly used for adults with cardiac arrest (CA) refractory to Advanced Cardiovascular Life Support (ACLS). Concerns exist that adding ECPR could worsen health inequities, defined as differences in health outcomes that are unfair or unjust. Current guidelines do not explicitly address this issue.
View Article and Find Full Text PDFPhotodynamic therapy with a novel photosensitizer inhibits DSS-induced ulcerative colitis in rats via the NF-κB signaling pathway.
Front Pharmacol
January 2025
Tianjin Key Laboratory of Biomedical Material, Institute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China.
Introduction: Ulcerative colitis (UC) is an inflammatory bowel disease characterized by inflammation and ulceration of the digestive tract.
Methods: Photodynamic therapy (PDT) with a novel photosensitizer LD was used to treat UC rat models to explore the therapeutic effect and mechanism of LD-PDT on UC. 16S ribosomal RNA was used to detect the composition of Gut microbiota.
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