A new spirostanol steroid, aspidiata A (), and a new spirostanol steroidal saponin, aspidiata B (), along with three known compounds, paris saponin VII (), daucosterol (), and (25)-spirostane-1,2,3,4,5,6-hexol (), were isolated from whole plants of collected in Vietnam. Their chemical structures were established by spectroscopic analysis and comparison with previously published data. Compound showed strong cytotoxicity against LU-1, Hep-G2, MCF-7, and KB human cancer cell lines with half maximal inhibitory concentration (IC) values ranging from 0.57 to 1.23 µM. Compound exhibited weak cytotoxic activity against the LU-1 cell line, with an IC value of 95.81 µM.
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