Schizotypal personality disorder (SPD) first appeared in the American Psychiatric Association diagnostic nosology in 1980, although its roots stretch back more than 100 years under labels such as borderline, ambulatory, and latent schizophrenia. SPD is unique in that it is conceptualized both as stable personality pathology and also as a milder manifestation of schizophrenia-spectrum psychopathology. The categorical operationalization of SPD has remained largely unchanged for the last 40 years, with emphasis on interpersonal deficits, cognitive and perceptual distortions, and odd and eccentric behaviors. The alternative model for personality disorders (AMPD) retained many of the aspects of SPD while offering a hybrid model that includes both disturbances in personality functioning and specific pathological personality traits. The present review examined the empirical literature on the success of the AMPD model in capturing SPD. Although research specifically examining AMPD SPD is limited, there is converging evidence that the six trait facets proposed for the AMPD SPD provide good coverage of SPD and correspond closely to criterion counts from the categorical SPD diagnosis. Furthermore, most studies find that the inclusion of additional facets not proposed for SPD do not account for appreciable variance. However, SPD offers a rather heterogeneous construct, and future studies should consider whether specifying positive, negative, and disorganized traits within the disorder might improve the clarity of the diagnosis. (PsycInfo Database Record (c) 2022 APA, all rights reserved).
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http://dx.doi.org/10.1037/per0000538 | DOI Listing |
Cytokine
January 2025
Collegium Medicum, Jan Kochanowski University in Kielce, 25-317 Kielce, Poland; Department of Endocrinology, Holy Cross Cancer Center, 25-734 Kielce, Poland.
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January 2025
Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.
Background And Aim: NK cells and NK-cell-derived cytokines were shown to regulate neutrophil activation in acute lung injury (ALI). However, the extent to which ALI regulates lung tissue-resident NK (trNK) activity and their molecular phenotypic alterations are not well defined. We aimed to assess the impact of 1,25-hydroxy-vitamin-D3 [1,125(OH)D] on ALI clinical outcome in a mouse model and effects on lung trNK cell activations.
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January 2025
Human-Computer Collaborative Robot Joint Laboratory of Anhui Province, Huainan, China.
To address the challenges of low detection accuracy of small objects and weak applicability of the multi-person fall action recognition applications, we propose a hybrid fall detection method based on modified YOLOv8s and AlphaPose called HFDMIA-Pose. Firstly, we use the modified Yolov8s as object detector. It uses SPD-Conv to preserve small object features and adds a small object detection layer, while using BCIOU as the loss function.
View Article and Find Full Text PDFAm J Physiol Lung Cell Mol Physiol
January 2025
Department of Pediatrics, The Pennsylvania State College of Medicine, Hershey, PA, USA.
Since its outbreak, the novel coronavirus (COVID-19) has significantly impacted the pediatric population. Pulmonary surfactant dysfunction has been linked to other respiratory diseases in children and COVID-19 in adults, but its role in COVID-19 severity remains unclear. We hypothesized that elevated surfactant protein (SP) levels and single nucleotide polymorphisms (SNPs) of SP genes are associated with severe COVID-19 in children.
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January 2025
Department of Clinical Laboratory, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders and Chongqing Key Laboratory of Pediatric Metabolism and Inflammatory Diseases, Chongqing, China.
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