Controlled-Alignment Patterns of Dipeptide Micro- and Nanofibers.

ACS Nano

Beijing National Laboratory for Molecular Sciences (BNLMS), CAS, Key Lab of Colloid, Interface and Chemical Thermodynamics, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.

Published: July 2022

AI Article Synopsis

  • Researchers developed a method to create and deposit ordered assemblies of the peptide diphenylalanine (FF) on flat surfaces using a dip-coating technique.
  • The assembly growth is driven by solvent evaporation from aqueous ammonia solutions, with different growth types influenced by process parameters like gas flow and withdrawal speed.
  • The study identifies conditions that lead to the formation of long, straight microfibers or shorter, curved nanofibers, as well as striped patterns that can be arranged in uniform arrays.

Article Abstract

Ordered assemblies of the peptide diphenylalanine (FF) are produced and deposited on planar substrates. The FF aggregate growth is achieved through precipitation from aqueous ammonia solutions induced by solvent evaporation. The applied dip-coating technique confines the FF assembly growth to a narrow zone near the three-phase contact. The growth was observed online by optical microscopy and was investigated systematically as a function of the process parameters. Depending on the external gas flow (to influence solvent evaporation), the withdrawal speed, the initial FF, and the initial ammonia concentrations, FF forms long, straight, and rigid microfibers and/or shorter, curved nanofibers. Under certain process conditions, the FF fibers can also aggregate into stripes. These can be deposited as large arrays of uniform stripes with regular widths and spacings. Scenarios leading to the various types of fibers and the stripe formation are presented and discussed in view of the experimental findings.

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Source
http://dx.doi.org/10.1021/acsnano.2c00443DOI Listing

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