Human papillomavirus (HPV) infection causes condyloma acuminata (CA). Podophyllin is the standard treatment. (), a medicinal plant, has potent anti-inflammatory and antiviral effects. cream is widely used in Thailand to treat the herpes simplex virus. We proposed that might also induce CA clearance. There are no studies of treatment of CA. This randomized controlled trial at Siriraj Hospital, Thailand, was conducted between January 2018 and December 2019. CA samples were obtained from 10 men with at least two CAs 1 centimeter apart. Each wart was randomized to a 4-week treatment with either or podophyllin. The participants were 24 to 72 years old. Most HPV types were low-risk HPVs (HPV 11, HPV 6). Median CA clearance with podophyllin was a 97% CA clearance with podophyllin and 82% with . may be an alternative treatment for CA.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246565 | PMC |
| http://dx.doi.org/10.1155/2022/1577716 | DOI Listing |
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