AI Article Synopsis
- Epitope spreading refers to the process where the immune response expands from an initial target (like a specific protein) to other similar or related targets within the same tissue or area.
- Subacute thyroiditis (SAT) and pemphigus vulgaris are autoimmune conditions that can occur simultaneously, suggesting a shared immune response mechanism.
- The molecular link between SAT and pemphigus vulgaris may involve epitope spreading, where the immune system's focus on thyroid proteins leads to the targeting of skin proteins, resulting in symptoms of both diseases.
Article Abstract
Epitope spreading phenomenon explaining the molecular link between subacute thyroiditis (SAT) and pemphigus vulgaris.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245171 | PMC |
| http://dx.doi.org/10.1002/agm2.12202 | DOI Listing |
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