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[Main changes in the «COVID-19 in paediatrics» clinical practice guideline]. | LitMetric

AI Article Synopsis

  • The text outlines updates to the "COVID-19 in Paediatrics" clinical practice guideline, comparing changes made from its 2021 version to the 2022 version.
  • Modifications were made using evidence-based medicine principles and the GRADE system, focusing on areas like epidemiology, diagnosis, prevention, treatment, and vaccines, with input from external reviewers.
  • Although the literature from the second year added some data, significant changes were primarily in vaccine research, and the emergence of the omicron variant indicates that further updates will be necessary.

Article Abstract

We present a summary of the main modifications to the «COVID-19 in Paediatrics» clinical practice guideline made from its initial version, published in 2021, and the version published in 2022. The document was developed following the structured steps of evidence-based medicine and applying the GRADE system to synthesize the evidence, assess its quality and, when appropriate, issue graded recommendations (based on the quality of the evidence, values and preferences, the balance between benefits, risks and costs, equity and feasibility). This update also includes the modifications proposed by external reviewers.We summarised the main modifications in the following sections: epidemiology, clinical features, diagnosis, prevention, treatment and vaccines. In relation to the body of knowledge achieved in the first year of the pandemic, the literature published in the second year contributed additional data, but without substantial modifications in many of the areas. The main changes took place in the field of vaccine research. This update was completed in December 2021, coinciding with the emergence of infections by the omicron variant, so the document will need to be updated in the future.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237022PMC
http://dx.doi.org/10.1016/j.anpedi.2022.06.015DOI Listing

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