Viewing the brain as a complex computer of simple neurons cannot account for consciousness nor essential features of cognition. Single cell organisms with no synapses perform purposeful intelligent functions using their cytoskeletal microtubules. A new paradigm is needed to view the brain as a scale-invariant hierarchy extending both upward from the level of neurons to larger and larger neuronal networks, but also downward, inward, to deeper, faster quantum and classical processes in cytoskeletal microtubules inside neurons. Evidence shows self-similar patterns of conductive resonances repeating in terahertz, gigahertz, megahertz, kilohertz and hertz frequency ranges in microtubules. These conductive resonances apparently originate in terahertz quantum dipole oscillations and optical interactions among pi electron resonance clouds of aromatic amino acid rings of tryptophan, phenylalanine and tyrosine within each tubulin, the component subunit of microtubules, and the brain's most abundant protein. Evidence from cultured neuronal networks also now shows that gigahertz and megahertz oscillations in dendritic-somatic microtubules regulate specific firings of distal axonal branches, membrane and synaptic activities. The brain should be viewed as a scale-invariant hierarchy, with quantum and classical processes critical to consciousness and cognition originating in microtubules inside neurons.
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http://dx.doi.org/10.3389/fnmol.2022.869935 | DOI Listing |
Asian J Psychiatr
January 2025
Centre for Brain Research, IISc Bangalore, India. Electronic address:
Background: Traumatic brain injury (TBI) can be primary/secondary injury which may culminate in cognitive impairment. This study aims to study the prevalence and to evaluate the cognition in participants afflicted with mild/moderate TBI.
Methodology: The study considered 1464 participants aged ≥ 45 years from Tata Longitudinal Study of Aging (TLSA).
Psychol Res Behav Manag
January 2025
Department of Psychology, Shaoxing University, Shaoxing, 312000, People's Republic of China.
Background: Stigma can not only threaten the self-identity of secondary vocational students, but also have negative effects on their mental health and behavior.
Objective: This study aimed to develop the Self-Stigma Scale for Secondary Vocational Students (SSS-SVS) and test its reliability and validity.
Patients And Methods: This study formed a scale based on the stigma conceptualization model and open questionnaire.
Adv Sci (Weinh)
January 2025
Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China.
Emotion processing is an integral part of everyone's life. The basic neural circuits involved in emotion perception are becoming clear, though the emotion's cognitive processing remains under investigation. Utilizing the stereo-electroencephalograph with high temporal-spatial resolution, this study aims to decipher the neural pathway responsible for discriminating low-arousal and high-arousal emotions.
View Article and Find Full Text PDFJ Gerontol A Biol Sci Med Sci
January 2025
Centro de Investigación Clínica Avanzada (CICA), Hospital Clínico Universidad de Chile.
Postoperative delirium (POD), an acute cognitive dysfunction linked to morbidity and mortality, is characterized by memory impairments and disturbances in consciousness, particularly in patients aged 65 and older. Neuroinflammation and NAD+ imbalance are key mechanisms behind POD, leading to synaptic and cognitive deterioration. However, how surgery contributes to POD and neuroinflammation remains unclear, and effective treatments are lacking.
View Article and Find Full Text PDFConscious Cogn
January 2025
Department of Psychological and Brain Sciences, University of California Santa Barbara, CA, USA.
Asking participants to Think Aloud is a common method for studying conscious experience, but it remains unclear whether this approach alters thought qualities-such as meta-awareness, rate of topic shifts, or the content of thoughts in task-absent conditions. To investigate this, we conducted two studies comparing thinking aloud to thinking silently. In Study 1, 111 participants alternated between 15-minute intervals of verbalizing and silently reflecting on their stream of consciousness in a counterbalanced design.
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