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Lymphatic Mapping and Sentinel Node Biopsy in High-Grade Uterine Cancers. | LitMetric

Lymphatic Mapping and Sentinel Node Biopsy in High-Grade Uterine Cancers.

Curr Oncol Rep

Department of Gynecologic Oncology and Reproductive Medicine, Division of Surgery, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 1362, Houston, TX, 77030, USA.

Published: November 2022

AI Article Synopsis

  • Sentinel lymph node (SLN) mapping is being recognized as a valuable technique for evaluating lymph nodes in patients with high-grade endometrial cancer, similar to its use in low-grade cases.
  • Recent studies show that SLN mapping has high detection rates and diagnostic accuracy, though surgeon experience is crucial for maintaining accuracy.
  • Future research is needed to compare long-term outcomes between SLN mapping and the traditional approach of systematic lymphadenectomy in high-grade endometrial cancer patients.

Article Abstract

Purpose Of Review: Sentinel lymph node (SLN) mapping has been adopted as an acceptable method of lymph node evaluation in the surgical staging for low-grade endometrial cancer. In this review, we analyze the literature on the utility of SLN mapping in high-grade endometrial cancer.

Recent Findings: SLN mapping in high-grade endometrial cancer demonstrates similar high detection rates and diagnostic accuracy as seen in low-grade endometrial cancers. However, obtaining sufficient operator experience (at least 30 cases) and following SLN mapping algorithm continues to be essential to preserving diagnostic accuracy. Although limited in retrospective study design and short-term follow-up, current studies have not demonstrated inferior survival outcomes of SLN mapping compared to traditional lymphadenectomy. SLN mapping is an acceptable and accurate method of lymph node evaluation in high-grade endometrial cancer. Future prospective studies are needed to evaluate long-term oncologic outcomes between SLN mapping and systematic lymphadenectomy in this patient population.

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Source
http://dx.doi.org/10.1007/s11912-022-01294-0DOI Listing

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