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Aortic Dissection Complicated by Mesenteric Malperfusion Syndrome Presenting As Hepatic Ischemia: A Case Report and Literature Review.
Cureus
November 2024
Internal Medicine and Diabetes and Endocrinology, Barking, Havering and Redbridge National Health Service (NHS) Hospital Trust, London, GBR.
Aortic dissection (AD) is a medical emergency that occurs as a result of a compromise in the structural integrity of the aorta. If left untreated, AD can have severe consequences such as organ dysfunction or even death. Malperfusion syndrome is a major complication of aortic dissection with mesenteric malperfusion syndrome being a rare but devastating form that can lead to mesenteric ischemia and is associated with poor prognosis despite timely management.
View Article and Find Full Text PDFBrain and brain blood vessels histological description in autopsies of fetuses/neonates born to mothers with hypertension during pregnancy. A case-control study.
Lancet Reg Health Am
January 2025
Department of Pathology, Hospital Universitario San Ignacio, Bogotá, Colombia.
Background: Children born to women with hypertension during pregnancy have a two to threefold increased risk of developing cognitive disorders compared to children born to women without hypertension. However, structural changes in the central nervous system of these children remain poorly understood. We aim to compare the brain histological findings from autopsies of neonates and fetuses born to women with and without hypertension during pregnancy.
View Article and Find Full Text PDFMalperfusion, Malperfusion Syndrome, and Mesenteric Ischemia in Aortic Dissection.
Semin Thorac Cardiovasc Surg
December 2024
Department of Cardiac Surgery, University of Michigan, Ann Arbor, Michigan. Electronic address:
Aortic malperfusion occurs in a significant percentage of patients with acute aortic dissection, and causes malperfusion syndrome, the clinical entity defined by end organ ischemia, in 10-33% of patients. Malperfusion syndrome can be rapidly lethal and can involve the coronary, cerebral, visceral, or lower extremity vessels. Depending on presentation, it may be appropriately and well treated with endovascular fenestration prior to definitive central aortic repair.
View Article and Find Full Text PDFPercutaneous management of cerebral malperfusion prior to surgery for acute type A dissection accompanied by severe common carotid artery stenosis.
Asian J Surg
November 2024
Department of Cardiovascular Surgery, The University of Hong Kong-Shenzhen Hospital, Guangdong, PR China. Electronic address:
Extracorporeal Off-Pump Antegrade Cerebral Perfusion in Reconstructive Surgery for Type A Aortic Dissection With Cerebral Malperfusion.
Cureus
October 2024
Department of Cardiovascular Medicine, RUDN University, Moscow, RUS.
Article Synopsis
- TAAD is a severe condition often complicated by CM, which can cause significant neurological damage; CPB and ACP are traditional methods used for cerebral protection during surgery but carry higher risks.
- This study investigates a new off-pump technique using an axillo-axillary shunt to maintain continuous blood flow to the brain during aortic arch surgery for patients with TAAD and CM.
- Results show that this innovative technique provided stable cerebral perfusion without new permanent neurological issues; however, some patients experienced temporary symptoms, and there was a low operative mortality rate of 5.6%.
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