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| http://dx.doi.org/10.1111/jocd.15208 | DOI Listing |
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Lichenoid paraneoplastic pemphigus in a patient presenting with follicular lymphoma: a review of the literature.
Arch Dermatol Res
November 2024
Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, 1295 NW 14th St, Miami, FL, 33125, USA.
Article Synopsis
- Paraneoplastic pemphigus (PNP) is a rare autoimmune blistering disease linked to cancer, typically presenting with severe mouth sores and varied skin eruptions.
- The case study details a patient with follicular lymphoma (FL) who developed symptoms of PNP, prompting a review of current treatment options and understanding of the disease.
- Despite potential remission from related cancers, PNP has a low 5-year survival rate, highlighting the urgent need for more research and suggesting that T cell immunosuppressive therapy might help FL patients with PNP.
Comparative immunohistochemical expression of Beta catenin and CD163 between dysplastic / non-dysplastic oral lichen planus and lichenoid lesions (EX-VIVO STUDY).
BMC Oral Health
September 2024
Oral & Maxillofacial Pathology, Faculty of Dentistry, Cairo University, Cairo, Egypt.
Article Synopsis
- Oral lichen planus and oral lichenoid lesions are chronic inflammatory conditions considered potentially malignant disorders, and their immune profiles were compared in this study.
- The research involved four study groups (dysplastic and non-dysplastic cases of both conditions), examining the immune expression of β-catenin and CD163 through immunohistochemistry.
- Results indicated a significant difference between groups and a moderate positive correlation between β-catenin and CD163, suggesting a link that could inform new treatment strategies for these oral conditions.
Oral Chronic Mucositis in a Known Lichen Planus Pigmentosus Patient.
Case Rep Dent
June 2024
Department of Oral Medicine Faculty of Dentistry Chulalongkorn University, Pathumwan, Bangkok 10330, Thailand.
Oral manifestations of mucocutaneous inflammatory diseases such as lichenoid dermatoses often affect the patient's quality of life through the symptoms of pain and burning sensation. In this case report, a patient with known lichen planus pigmentosus (LPP), a variant of lichenoid dermatoses that rarely affect oral mucosa, presented with chronic pain in the oral cavity for 2 months. Her intraoral examination revealed multiple pseudomembranous ulcers with erythematous areas and white striae similar to erosive lichen planus.
View Article and Find Full Text PDFOral lichen planus and lichenoid lesions - challenges and pitfalls for the general dental practitioner.
Br Dent J
February 2024
Institute of Dentistry, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, AB25 2ZR, UK.
Lichen planus is a chronic, mucocutaneous inflammatory condition which, due to its prevalence, will be familiar to the dental profession. However, diverse forms of presentation, important differential diagnosis, potential malignant change and monitoring requirements often result in challenges for those in primary care. This paper looks to examine these challenges and provide information to support those who are involved in recognition and management of patients with lichen planus.
View Article and Find Full Text PDFThalidomide for management of refractory oral mucosal diseases.
Oral Surg Oral Med Oral Pathol Oral Radiol
April 2024
Division of Oral Medicine and Dentistry, Brigham and Women's Hospital, Boston, MA USA; Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, MA, USA.
Background: Thalidomide has anti-inflammatory properties and has been used off-label for multiple mucocutaneous disorders, but its application in managing refractory oral mucosal diseases is unclear. This study aimed to review the efficacy and safety of thalidomide in treating various oral mucosal disorders refractory to conventional therapies.
Methods: The medical records of patients who were prescribed thalidomide from 2002 through 2021 for oral mucosal disorders were reviewed.
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